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General Information
Symbol
Dmel\CamUAS.cWa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Wang
FlyBase ID
FBal0141860
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-CaM
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of wild type Cam.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Cam7/Camn339 animals rescued to adulthood by expression of CamScer\UAS.cWa under the control of Scer\GAL4how-24B are behaviourally abnormal; they fail to climb after being gently knocked to the bottom of a vial, and they show poor flight and a reduced ability to right themselves after a brief vortexing. The initial stages of male courtship are normal, but the rescued males cannot bend their abdomens sufficiently to achieve penetration.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of CamScer\UAS.cWa and NosScer\UAS.cMa under the control of Scer\GAL4ey-OK107 does not significantly affect axon regrowth in the mushroom body gamma-lobe.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

The lethality and pupariation defects seen in Cam7/Camn339 animals are rescued by expression of CamScer\UAS.cWa under the control of Scer\GAL4how-24B; the pupal cases are morphologically wild type and have more normal length:width ratios, almost all of the rescued pupae eclose and no aberrant pharate head structures are seen. The lethality and pupariation defects seen in Cam7/Camn339 animals are not rescued by expression of CamScer\UAS.cWa under the control of Scer\GAL4elav.PLu or Scer\GAL4sca.PU. The sluggish larval locomotion of Cam7/Camn339 animals is incompletely rescued by expression of CamScer\UAS.cWa under the control of Scer\GAL4how-24B or Scer\GAL4elav.PLu. The spontaneous backward movement seen in homozygous Camn339 larvae is not rescued by expression of CamScer\UAS.cWa under the control of Scer\GAL4how-24B or Scer\GAL4sca.PU. The spontaneous backward movement seen in homozygous Camn339 larvae is rescued by expression of CamScer\UAS.cWa under the control of Scer\GAL4elav.PLu, although the larvae are still sluggish.

Expression of CamScer\UAS.cWa under the control of Scer\GAL4how-24B rescues the developmental defects and lethality of Cam7/Camn339 mutants.

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
CamScer\UAS.cWa
CamUAS.cWa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Wang
Secondary FlyBase IDs
    References (4)