FlyBase Allele Report: Dmel\wg[SH1281]

General Information

Symbol

Dmel\wg^SH1281

Species

D. melanogaster

Name

FlyBase ID

FBal0143718

Feature type

allele

Associated gene

Dmel\wg

Associated Insertion(s)

P{lacW}wg^SH1281

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Oh et al., 2003)

Progenitor genotype

Associated Insertion(s)

P{lacW}wg^SH1281

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:7,306,989..7,307,139

(Vicidomini et al., 2015, Oh et al., 2003)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Oh et al., 2003)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

wg^SH1281 is an enhancer of visible phenotype of Nop60B^GD16822, Scer\GAL4^bi.PU

(Vicidomini et al., 2015)

Suppressor of

Statement

Reference

wg^SH1281 is a suppressor of increased cell death | third instar larval stage phenotype of Nop60B^GL00555, Scer\GAL4^bi.PU

(Vicidomini et al., 2015)

Other

Statement

Reference

Nop60B^GD16822, wg^SH1281 has majority die during P-stage phenotype

(Vicidomini et al., 2015)

Phenotype Manifest In

Enhancer of

Statement

Reference

wg^SH1281 is an enhancer of wing phenotype of Nop60B^GD16822, Scer\GAL4^bi.PU

(Vicidomini et al., 2015)

Suppressor of

Statement

Reference

wg^SH1281 is a suppressor of wing disc | third instar larval stage phenotype of Nop60B^GL00555, Scer\GAL4^bi.PU

(Vicidomini et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

Most Scer\GAL4^bi.PU>Nop60B^GD16822 larvae carrying wg^SH1281 die at the pupal stage, and adult escapers show underdeveloped deformed wings (worse than is seen in Scer\GAL4^bi.PU>Nop60B^GD16822 adults).

wg^SH1281 suppresses apoptosis-induced increases in proliferative activity in Scer\GAL4^bi.PU>Nop60B^GL00555 wing discs.

(Vicidomini et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

122098

w^*; P{lacW}wg^SH1281

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

l(2)SH1281^SH1281

wg^SH1281

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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