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General Information
Symbol
Dmel\Pten2L100
Species
D. melanogaster
Name
FlyBase ID
FBal0144651
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Mutagen
    Nature of the Allele
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference

    Mutation outside of the open reading frame.

    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Pten117/Pten2L100 mutant larvae and adult flies are larger than wild-type controls under normal food conditions. The prospective adult tissues, the eye and wing imaginal discs are larger than in controls. These larvae are highly sensitive to a reduction in yeast content, and although still larger, they do not survive to pupariation when reared on 10g/l yeast food. Pten117/Pten2L100 mutant larvae reared on 100g/l yeast food at 39% larger than controls reared on 100g\l yeast food.

    Weak temperature sensitive mutation. Pten2L100/Pten117 larvae, pupae and adults are substantially increased in size compared to control larvae. Pten2L100/Pten117 adults are hypersensitive to starvation conditions compared to wild type.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Suppressor of
    Statement
    Reference
    NOT Suppressor of
    Statement
    Reference

    Pten2L100/Pten117 is a non-suppressor of lethal phenotype of Pi3K92Eunspecified

    Other
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (4)
    Reported As
    Name Synonyms
    Secondary FlyBase IDs
      References (6)