FlyBase Allele Report: Dmel\Def[UAS.cTa]

General Information

Symbol

Dmel\Def^UAS.cTa

Species

D. melanogaster

Name

FlyBase ID

FBal0145092

Feature type

allele

Associated gene

Dmel\Def

Associated Insertion(s)

Carried in Construct

P{UAS-Def.T}

Also Known As

UAS-Def

Key Links

Transgenic product class

wild_type

(Tzou et al., 2002)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Tzou et al., 2002)

Mutagen

in vitro construct

(Tzou et al., 2002)

Progenitor genotype

Carried in construct

P{UAS-Def.T}

Cytology

Description

Expression of Def (398-bp HindIII-KpnI fragment) is under the control of UASt sequences.

(Tzou et al., 2002)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Def

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable, with Scer\GAL4^da.G32

(Tzou et al., 2002)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Scer\GAL4^apolpp.PB, Def^UAS.cTa, Def^SK3 is an enhancer of neoplasia | larval stage phenotype of dlg1^A40.2

(Parvy et al., 2019)

Scer\GAL4^apolpp.PB, imd^KK109863, Def^UAS.cTa is an enhancer of neoplasia | larval stage phenotype of dlg1^A40.2

(Parvy et al., 2019)

Suppressor of

Statement

Reference

Scer\GAL4^apolpp.PB, Def^UAS.cTa, Def^SK3 is a suppressor of increased cell death | larval stage phenotype of dlg1^A40.2

(Parvy et al., 2019)

Scer\GAL4^apolpp.PB, imd^KK109863, Def^UAS.cTa is a suppressor | partially of increased cell death | larval stage phenotype of dlg1^A40.2

(Parvy et al., 2019)

Scer\GAL4^apolpp.PB, Def^UAS.cTa, Myd88^GD9716 is a suppressor | partially of increased cell death | larval stage phenotype of dlg1^A40.2

(Parvy et al., 2019)

Phenotype Manifest In

Enhancer of

Statement

Reference

Scer\GAL4^apolpp.PB, Def^UAS.cTa, Def^SK3 is an enhancer of wing disc phenotype of dlg1^A40.2

(Parvy et al., 2019)

Scer\GAL4^apolpp.PB, imd^KK109863, Def^UAS.cTa is an enhancer of wing disc phenotype of dlg1^A40.2

(Parvy et al., 2019)

Suppressor of

Statement

Reference

Scer\GAL4^apolpp.PB, Def^UAS.cTa, Def^SK3 is a suppressor of wing disc phenotype of dlg1^A40.2

(Parvy et al., 2019)

Scer\GAL4^apolpp.PB, imd^KK109863, Def^UAS.cTa is a suppressor | partially of wing disc phenotype of dlg1^A40.2

(Parvy et al., 2019)

Scer\GAL4^apolpp.PB, Def^UAS.cTa, Myd88^GD9716 is a suppressor of wing disc phenotype of dlg1^A40.2

(Parvy et al., 2019)

Additional Comments

Genetic Interactions

Statement

Reference

Scer\GAL4^apolpp.PB-driven expression of Def^UAS.cTa in Def^SK3, dlg1^A40.2 double mutants, imd^KK109863, dlg1^A40.2 double mutants, or Myd88^GD9716, dlg1^A40.2 double mutants partially re-establishes the original dlg1^A40.2 phenotypes.

(Parvy et al., 2019)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Def^Scer\UAS.cTa

Def^UAS.cTa

Name Synonyms

(Tzou et al., 2002)

Secondary FlyBase IDs

References (6)

Report Sections

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