FlyBase Allele Report: Dmel\dimm[KG02598]

General Information

Symbol

Dmel\dimm^KG02598

Species

D. melanogaster

Name

FlyBase ID

FBal0147206

Feature type

allele

Associated gene

Dmel\dimm

Associated Insertion(s)

P{SUPor-P}dimm^KG02598

Carried in Construct

Also Known As

dimm^p1

Key Links

Genomic Maps

JBrowse

Allele class

hypomorphic allele - genetic evidence

hypomorphic allele - molecular evidence

Mutagen

P-element activity

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Hewes et al., 2003)

hypomorphic allele - molecular evidence

(Hewes et al., 2003)

Mutagen

P-element activity

(Hewes et al., 2003)

Progenitor genotype

Associated Insertion(s)

P{SUPor-P}dimm^KG02598

Cytology

Description

The P{SUPor-P} insertion is 111bp upstream of the dimm gene.

(Hewes et al., 2003)

Allele components

Component

Use(s)

Inserted element

P{SUPor-P}

insertional mutagenesis tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:21,331,662..21,331,662 [-]

(Park et al., 2004, Hewes et al., 2003)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy

(Bivik et al., 2015)

lethal (with Df(2L)Rev4)

(Hewes et al., 2003)

lethal (with dimm^R6)

(Hewes et al., 2003)

lethal (with dimm^Rev8)

(Hewes et al., 2003)

lethal | recessive

(Hewes et al., 2003)

Phenotype Manifest In

apterous-expressing neuron of the lateral cluster of the thorax

(Bivik et al., 2015)

apterous-expressing neuron of the lateral cluster of the thorax Ap4

(Bivik et al., 2015)

Detailed Description

Statement

Reference

Mutants show loss of expression of P{FMRFa-EGFP.Tv}, a marker for the six Ap4 neurons in the developing ventral nerve cord, and loss of expression of eya, which identifies the four Ap cluster neurons.

(Bivik et al., 2015)

The number of SE2 neurons is normal in dimm^KG02598 mutant animals.

(Losada-Pérez et al., 2010)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Complements

crc^R1

(Hewes et al., 2003)

crc¹

(Hewes et al., 2003)

crc⁹²⁹

(Hewes et al., 2003)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

13759

y¹; P{SUPor-P}dimm^KG02598/CyO; ry⁵⁰⁶

Kyoto

111562

y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{5xglBS-lacZ.38-1}TPN1; P{SUPor-P}dimm^KG02598 P{neoFRT}40A/CyO y⁺

Notes on Origin

Discoverer

Comments

The neuropeptide expression phenotype is revertable on excision of the P{SUPor-P}.

(Hewes et al., 2003)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

2598

(Hewes et al., 2003)

dimm^KG02598

dimm^P1

(Stratmann and Thor, 2017, Berndt et al., 2015, Bivik et al., 2015, Losada-Pérez et al., 2010, Miguel-Aliaga et al., 2008)

dimm^p1

(Baumgardt et al., 2007)

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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