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General Information
Symbol
Dmel\Pi3K92E5W3
Species
D. melanogaster
Name
FlyBase ID
FBal0152313
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Dp1105W3
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 1 )
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Homozygous Pi3K92E5W3 mutant adult flies have a reduced body weight compared to heterozygous controls.

    Lipid and carbohydrate content are not increased in homozygous Pi3K92E5W3 mutant flies compared to controls.

    Homozygous Pi3K92E5W3 mutant flies exhibit defective electroretinogram (ERG) readings.

    Cholinesterase activity is significantly reduced in homozygous Pi3K92E5W3 mutant flies compared to controls.

    Pi3K92E2H1/Pi3K92E5W3 mutant adult flies have a reduced body weight compared to heterozygous controls. Wing area is also reduced compared to controls.

    Lipid and carbohydrate content are increased in Pi3K92E2H1/Pi3K92E5W3 mutant flies compared to controls.

    Pi3K92E2H1/Pi3K92E5W3 mutant flies exhibit defective electroretinogram (ERG) readings.

    Cholinesterase activity is not significantly reduced in Pi3K92E2H1/Pi3K92E5W3 mutant flies compared to controls.

    Pi3K92EA/Pi3K92E5W3 mutant adult flies have a reduced body weight compared to heterozygous controls.

    Lipid and carbohydrate content are increased in Pi3K92EA/Pi3K92E5W3 mutant flies compared to controls.

    Pi3K92EA/Pi3K92E5W3 mutant flies exhibit defective electroretinogram (ERG) readings.

    Cholinesterase activity is not significantly reduced in Pi3K92EA/Pi3K92E5W3 mutant flies compared to controls.

    Head capsule reduced - pinhead phenotype.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Suppressed by
    Statement
    Reference
    Enhancer of
    Statement
    Reference

    Pi3K92E5W3/Pi3K92E[+] is an enhancer of size defective | adult stage phenotype of sl2

    Suppressor of
    Statement
    Reference
    Phenotype Manifest In
    Suppressed by
    Statement
    Reference
    Enhancer of
    Statement
    Reference

    Pi3K92E5W3/Pi3K92E[+] is an enhancer of wing blade phenotype of sl2

    Suppressor of
    Statement
    Reference

    Pi3K92E5W3/Pi3K92E[+] is a suppressor | partially of wing vein | ectopic phenotype of sl2

    Additional Comments
    Genetic Interactions
    Statement
    Reference

    One copy of Pi3K92E5W3 enhances the reduction in wing blade area seen in homozygous sl2 males.

    One copy of Pi3K92E5W3 partially suppresses the ectopic wing vein phenotype seen in sl2 homozygotes.

    One copy of Pi3K92E5W3 partially suppresses the percentage of sl2 mutant ommatidia that contain extra R7 photoreceptors.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Name Synonyms
    Secondary FlyBase IDs
      References (3)