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General Information
Symbol
Dmel\S48-5
Species
D. melanogaster
Name
FlyBase ID
FBal0155935
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    S48-5 heterozygous mutants display a strong eye roughening phenotype and approximately 10% of ommatidia display orientation defects. Programmed cell death in the pupal eye disc (42 hours after pupal formation) is defective and a loss of interommatidial cells is observed.

    S48-5/+ animals show a mild loss of photoreceptors and ommatidial rotation abnormalities.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Enhanced by
    Statement
    Reference

    S48-5 has ommatidium phenotype, enhanceable by Ras85De2F

    S48-5 has ommatidium phenotype, enhanceable by pnut02502

    S48-5 has ommatidium phenotype, enhanceable by pnutXP

    S48-5 has ommatidium phenotype, enhanceable by shg2

    S48-5 has ommatidium phenotype, enhanceable by spi1

    S48-5 has ommatidium phenotype, enhanceable by spi259

    S48-5 has ommatidium phenotype, enhanceable by stanE59

    S48-5 has ommatidium phenotype, enhanceable by zip02957

    S48-5 has ommatidium phenotype, enhanceable by zip1

    S48-5 has ommatidium phenotype, enhanceable by Egfrt1

    S48-5 has ommatidium phenotype, enhanceable by capt06955

    S48-5 has ommatidium phenotype, enhanceable by chic01320

    S48-5 has ommatidium phenotype, enhanceable by cno2

    S48-5 has ommatidium phenotype, enhanceable by cno3

    Suppressor of
    Statement
    Reference

    S[+]/S48-5 is a suppressor | partially of ommatidium phenotype of ecspok

    Additional Comments
    Genetic Interactions
    Statement
    Reference

    The ommatidial rotation defects observed in ecspok hemizygous adult eyes are partially suppressed by S48-5/+.

    S48-5/spi259 mutants show 37.83%+-13.35 misrotated ommatidia compared to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/spi1 mutants show 40.04%+-3.7 misrotated ommatidia compared

    to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/grk3 mutants show 3.14%+-2.58 misrotated ommatidia compared

    to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/vnaddC6 mutants show 10.02%+-3.27 misrotated ommatidia

    compared to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/argosrlt mutants show 3.74%+-1.99 misrotated ommatidia

    compared to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/Egfrt1 mutants show 41.52%+-7.24 misrotated ommatidia

    compared to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/Ras85De2F mutants show 58.05%+-4.57 misrotated ommatidia

    compared to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/cno2 mutants show 40.56%+-7.99 misrotated ommatidia compared

    to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/cno3 mutants show 43.24%+-8.67 misrotated ommatidia compared

    to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/nmoP1 mutants show 17.38%+-5.39 misrotated ommatidia

    compared to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/shg2 mutants show 40.56%+-5.21 misrotated ommatidia compared

    to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/arm2 mutants show 12/43%+-5.66 misrotated ommatidia compared

    to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/stanE59 mutants show 45.59%+-7.32 misrotated ommatidia

    compared to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/wb09437 mutants show 13.2%+-3.05 misrotated ommatidia

    compared to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/wb4418 mutants show 7.17%+-0.60 misrotated ommatidia

    compared to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/mysunspecified mutants show 4.44%+-2.59 misrotated ommatidia

    compared to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/mys1 mutants show 7.64%+-3.82 misrotated ommatidia compared

    to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/ena02029 mutants show 7.77%+-2.95 misrotated ommatidia

    compared to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/pnutXP mutants show 24.58%+-5.90 misrotated ommatidia

    compared to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/pnut02502 mutants show 20.07%+-11.25 misrotated ommatidia

    compared to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/zip02957 mutants show 34.60%+-4.71 misrotated ommatidia

    compared to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/zip1 mutants show 19.34%+-7.06 misrotated ommatidia compared

    to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/Khc8 mutants show 10.38%+-5.72 misrotated ommatidia compared

    to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/Khck13314 mutants show 2.87%+-2.04 misrotated ommatidia

    compared to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/ck13 mutants show 5.41%+-2.22 misrotated ommatidia compared

    to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/capt06955 mutants show 34.19%+-8.94 misrotated ommatidia

    compared to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/kst01318 mutants show 5.62%+-1.13 misrotated ommatidia

    compared to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/scaBP1 mutants show 9.75%+-3.06 misrotated ommatidia

    compared to 9.55%+-1.43 seen in S48-5 mutants alone.

    S48-5/chic01320 mutants show 21.90%+-5.89 misrotated ommatidia

    compared to 9.55%+-1.43 seen in S48-5 mutants alone.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
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    Mutant
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    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Name Synonyms
    Secondary FlyBase IDs
      References (2)