FB2026_02 , released June 18, 2026
Allele: Dmel\Pcyt1299
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General Information
Symbol
Dmel\Pcyt1299
Species
D. melanogaster
Name
FlyBase ID
FBal0156790
Feature type
allele
Associated gene
Dmel\Pcyt1
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Weber et al., 2003)
Mutagen
Delta2-3 transposase
(Gupta and Schupbach, 2003)
Progenitor genotype
Pcyt1BN81
(Gupta and Schupbach, 2003)
Caused by aberration
Df(3L)Pcyt1299
Cytology
Description

Imprecise excision has created a deletion. Cct1 has been deleted completely.

(Gupta and Schupbach, 2003)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous Df(3L)Cct1299 (which are also deficient for Cct2) germ-line clones do not give a loss of female germline stem cell phenotype. When Df(3L)Cct1299 somatic clones are made in the follicle cells, no mis-positioning of the oocyte is seen. Eggs laid by Cct1124/Cct1299 females have a shortened operculum.

      (Gupta and Schupbach, 2003)

      First larval instar Garland cells of Cct1299 mutants show increased endocytosis, notably in the number of clathrin-coated pits and clathrin-coated vesicles and a subsequent enlargement of the late endosome, compared to wild-type cells. Traffic to the lysosome is not affected.

      (Weber et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Pcyt1299/Cct1[+] is an enhancer of wing phenotype of N55e11

      (Weber et al., 2003)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The Cct1299 allele dominantly enhances the notched wing phenotype seen in N55e11/+ flies.

      (Weber et al., 2003)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Cct1299
      Pcyt1299
      Name Synonyms
      Secondary FlyBase IDs
        References (2)