FlyBase Allele Report: Dmel\BG02257[BG02257]

General Information

Symbol

Dmel\BG02257^BG02257

Species

D. melanogaster

Name

FlyBase ID

FBal0157272

Feature type

allele

Associated gene

BG02257

Associated Insertion(s)

P{GT1}BG02257^BG02257

Carried in Construct

Also Known As

BG02257

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{GT1}BG02257^BG02257

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GT1}

gene trap

polyA trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Male and female BG02257^BG02257 mutants show an increased lifespan compared to controls.

(Magwire et al., 2010)

Lifespan and resistance to heat stress are significantly increased compared to controls in both males and females.

Resistance to starvation is significantly increased in males, but significantly decreased in females compared to controls.

Flies show no significant difference in trehalose preference index compared to controls.

(Rollmann et al., 2006)

Homozygous males show a significant increase in starvation resistance compared to controls.

(Harbison et al., 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

BG02257^BG02257 has abnormal starvation stress response | male phenotype, non-enhanceable by foxo^BG01573

(Rollmann et al., 2006)

BG02257^BG02257 has abnormal starvation stress response phenotype, non-enhanceable by foxo^BG01018

(Rollmann et al., 2006)

Suppressed by

Statement

Reference

BG02257^BG02257 has abnormal starvation stress response | female phenotype, suppressible by foxo^BG01573

(Rollmann et al., 2006)

BG02257^BG02257 has long lived | female phenotype, suppressible by foxo^BG01018

(Rollmann et al., 2006)

BG02257^BG02257 has long lived | male phenotype, suppressible by foxo^BG01018

(Rollmann et al., 2006)

BG02257^BG02257 has long lived | female phenotype, suppressible by foxo^BG01573

(Rollmann et al., 2006)

BG02257^BG02257 has long lived | male phenotype, suppressible by foxo^BG01573

(Rollmann et al., 2006)

NOT suppressed by

Statement

Reference

BG02257^BG02257 has abnormal starvation stress response | male phenotype, non-suppressible by foxo^BG01573

(Rollmann et al., 2006)

BG02257^BG02257 has abnormal starvation stress response phenotype, non-suppressible by foxo^BG01018

(Rollmann et al., 2006)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

BG02257

(Harbison et al., 2004)

BG02257^BG02257

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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