FB2026_02 , released June 18, 2026
Allele: Dmel\sra687
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General Information
Symbol
Dmel\sra687
Species
D. melanogaster
Name
FlyBase ID
FBal0175443
Feature type
allele
Associated gene
Dmel\sra
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Horner, 2006)
Mutagen
Delta2-3 transposase
(Singh et al., 2005)
P-element activity
(Horner, 2006)
Progenitor genotype
sraEP3462
(Horner, 2006)
Cytology
Description

Imprecise excision of the P{EP} element, resulting in a 1019bp deletion that spans the 5' UTR and intron of the sra gene.

(Horner, 2006)

Consists of a 1019bp deletion that removes the 5' end of the sra gene.

(Singh et al., 2005)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      sra687/Df(3R)sbd45 eggs are fertilized by sperm as the sperm nucleus can be observed inside the egg. However, the male pronucleus in fertilized eggs is much smaller than that of fully decondensed wild-type male pronuclei seen prior to pronuclear fusion. The sperm nucleus in these eggs becomes arrested in a pre-S phase, premitotic state. Neither sperm asters, nor any organized microtubule system associated with sperm nuclei can be observed in sra687/Df(3R)sbd45 eggs.

      (Horner et al., 2006)

      Eggs laid by sra687/Df(3R)sbd45 and sra687/sra619 mothers arrest during anaphase of the first meiotic division.

      The vitelline membranes of eggs laid by sra687/Df(3R)sbd45 and sra687/sra619 mothers are cross-linked.

      (Horner, 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Enhancer of
      Statement
      Reference

      sra687 is a non-enhancer of phenotype of bcd6

      (Singh et al., 2005)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Bin1R7-18/+, sra687/+ females are fertile.

      (Horner, 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      sra619

      (Horner, 2006)
      Rescued by

      sra687 is rescued by sracHa

      (Horner, 2006)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      sra687
      (Horner, 2006)
      sra687
      (Cui et al., 2008, Sackton et al., 2007, Horner et al., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)