UAS sequences drive expression Crk coding sequences (from GenBank:NM143651 nucleotides 387 to 976) repeated in dyad symmetry.
border follicle cell, with Scer\GAL4slbo.2.6
thorax, with Scer\GAL4pnr-MD237
Scer\GAL4slbo.2.6-mediated expression of CrkdsRNA.Scer\UAS results in defects in border cell migration.
When CrkdsRNA.Scer\UAS is driven by Scer\GAL4pnr-MD237 mutant adults exhibit defects in thorax closure. This phenotype is dose dependant.
CrkdsRNA.UAS, Scer\GAL4slbo.2.6 has border follicle cell phenotype, enhanceable by mbcdsRNA.UAS, Scer\GAL4slbo.2.6
CrkdsRNA.UAS, Scer\GAL4slbo.2.6 is an enhancer of border follicle cell phenotype of Scer\GAL4slbo.2.6, mbcdsRNA.UAS
Co-expression of mbcdsRNA.Scer\UAS and CrkdsRNA.Scer\UAS using Scer\GAL4slbo.2.6 increases the severity and penetrance of the border cell migration defects compared to when either transgene is expressed alone, but only slightly.