FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ActnRpS27A.PD
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General Information
Symbol
Dmel\ActnRpS27A.PD
Species
D. melanogaster
Name
Ribosomal protein S27A promoter construct of Dubreuil
FlyBase ID
FBal0176423
Feature type
allele
Associated gene
Dmel\Actn
Associated Insertion(s)
Carried in Construct
P{RpS27A-Actn.D}
Also Known As
B22
Key Links
Transgenic product class
wild_type
(Dubreuil and Wang, 2000)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Dubreuil and Wang, 2000)
Mutagen
in vitro construct
(Wahlstrom et al., 2004, Dubreuil and Wang, 2000)
Progenitor genotype
Carried in construct
P{RpS27A-Actn.D}
Cytology
Description

An RpS27A promoter drives expression of the 104kD adult muscle isoform of Actn.

(Dubreuil and Wang, 2000)
Allele components
Component
Use(s)
Regulatory region(s)
RpS27A
Encoded product / tool
Actn
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      actin filament bundle & egg chamber

      (Wahlstrom et al., 2006)
      Detailed Description
      Statement
      Reference

      Expression of ActnRpS27A.PD results in the formation of a dense layer of actin fibers with some abnormally thick actin bundles in the egg chamber at stages 9 and 10A. At late stage 11, the dorsal appendage cells of ActnRpS27A.PD-expressing egg chambers produce prominent spikes, not seen in wild-type cells.

      (Wahlstrom et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      When ActnRpS27A.PD is expressed in a Scer\GAL4GR1>btl::EgfrScer\UAS.T:λ\cI-DD background, all basal actin fibers are of follicle cells are transformed into a single branched or unbranched F-actin bundle.

      (Wahlstrom et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ActnRpS27A.PD
      Name Synonyms
      Ribosomal protein S27A promoter construct of Dubreuil
      (Dubreuil and Wang, 2000)
      Secondary FlyBase IDs
        References (3)