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General Information
Symbol
Dmel\fruGAL4.P1.D
Species
D. melanogaster
Name
FlyBase ID
FBal0179808
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
fruGAL4, fru-GAL4, fruGAL4.P1
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

The loxP cassette containing the Avic\GFPGMR.PS marker has been excised. This results in a fru locus in which the endogenous fru P1 promoter drives expression of GAL4 instead of the fru[M] isoform. A transcriptional stop signal and a single loxP site remain downstream of the GAL4 open reading frame.

Insertion components
TI{GAL4}fruGAL4.P1.D
Product class / Tool use(s)
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

fruGAL4.P1.D homozygous males court other males, sometimes forming chains that incorporate both wild-type and fruGAL4.P1.D/fruGAL4.P1.D animals.

fruGAL4.P1.D homozygous males court wild type and fruGAL4.P1.D/fruGAL4.P1.D flies with similar intensity.

The male-female courtship index of fruGAL4/fruGAL4 males is not significantly reduced compared to wild-type, but male fertility drops over 50%. The male-female courtship index of males carrying fruGAL4 in trans to fru3, fru3, or fruAJ96u3 is significantly reduced, and fertility is reduced to around 20% of wild-type. Males of all these males score highly in assays for male-male courtship assays (courtship index with single wild-type males and chaining with males of their own genotype).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

Photoactivation of fru-expressing neurons in headless females expressing Rnor\P2rx2Scer\UAS.cLa under the control of Scer\GAL4fru-GAL4 in a fruM/fruGAL4 background produces courtship songs with acoustic characteristics similar to those seen in headless males expressing Rnor\P2rx2Scer\UAS.cLa under the control of Scer\GAL4fru-GAL4 in a fru[+] background. Recordings of these courtship songs substitute fully for the songs of courting males in an assay where the song is played back to fly pairs consisting of a wingless male (which cannot produce a courtship song) and a virgin female).

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (7)
References (19)