FlyBase Allele Report: Dmel\Duox[UAS.cHa]

General Information

Symbol

Dmel\Duox^UAS.cHa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Ha

FlyBase ID

FBal0190278

Feature type

allele

Associated gene

Dmel\Duox

Associated Insertion(s)

Carried in Construct

P{UAS-Duox.H}

Also Known As

UAS-DUOX

Key Links

Transgenic product class

wild_type

(Ha et al., 2005)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Ha et al., 2005)

Mutagen

in vitro construct

(Ha et al., 2005)

Progenitor genotype

Carried in construct

P{UAS-Duox.H}

Cytology

Description

UASt regulatory sequences drive expression of full length Duox.

(Ha et al., 2005)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Duox

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates leukemia

modeled by mxc¹

(Kinoshita et al., 2022)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^He.PZ/Duox^UAS.cHa is a suppressor | partially of hyperplasia | larval stage phenotype of mxc¹

(Kinoshita et al., 2022)

Duox^UAS.cHa, Scer\GAL4^da.G32 is a suppressor of abnormal immune response phenotype of Atf-2^RNAi.UAS, Scer\GAL4^da.G32

(Ha et al., 2009)

Duox^UAS.cHa, Scer\GAL4^da.G32 is a suppressor of abnormal immune response phenotype of Mekk1^GD9945, Scer\GAL4^da.G32

(Ha et al., 2009)

Duox^UAS.cHa, Scer\GAL4^da.G32 is a suppressor of abnormal immune response phenotype of Scer\GAL4^da.G32, p38a^RNAi.UAS

(Ha et al., 2009)

Duox^UAS.cHa, Scer\GAL4^da.G32 is a suppressor of abnormal immune response phenotype of Scer\GAL4^da.G32, lic^RNAi.UAS

(Ha et al., 2009)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^He.PZ/Duox^UAS.cHa is a suppressor | partially of embryonic/larval lymph gland | larval stage phenotype of mxc¹

(Kinoshita et al., 2022)

Additional Comments

Genetic Interactions

Statement

Reference

The reduced survival of flies expressing Atf-2^{dsRNA.Scer\UAS} under the control of Scer\GAL4^da.G32 that have been fed Erwinia carotovora carotovora strain 15 is suppressed by co-expression of Duox^Scer\UAS.cHa.

The reduced survival of flies expressing Mekk1^GD9945 under the control of Scer\GAL4^da.G32 that have been fed Erwinia carotovora carotovora strain 15 is suppressed by co-expression of Duox^Scer\UAS.cHa.

The reduced survival of flies expressing Mpk2^{dsRNA.Scer\UAS} under the control of Scer\GAL4^da.G32 that have been fed Erwinia carotovora carotovora strain 15 is suppressed by co-expression of Duox^Scer\UAS.cHa.

The reduced survival of flies expressing lic^{dsRNA.Scer\UAS} under the control of Scer\GAL4^da.G32 that have been fed Erwinia carotovora carotovora strain 15 is suppressed by co-expression of Duox^Scer\UAS.cHa.

(Ha et al., 2009)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^da.G32/Duox^UAS.cHa rescues Duox^RNAi.UAS

(Ha et al., 2009)

Scer\GAL4^da.G32/Duox^UAS.cHa rescues Duox^RNAi.UAS

(Ha et al., 2005)

Duox^UAS.cHa/Scer\GAL4^cad-em459 rescues Duox^RNAi.UAS

(Ha et al., 2005)

Comments

The reduced survival of flies expressing Duox^{dsRNA.Scer\UAS} under the control of Scer\GAL4^da.G32 that have been fed Erwinia carotovora carotovora strain 15 is suppressed by co-expression of Duox^Scer\UAS.cHa.

(Ha et al., 2009)

The survival rates of flies expressing Duox^{dsRNA.Scer\UAS} under the control of Scer\GAL4^cad-em459 after natural infection with "Ecc15" (P.carotovorum.carotovorum) are markedly improved if they co-express Duox^Scer\UAS.cHa. The persistence of ingested "Ecc15" (P.carotovorum.carotovorum) bacteria that is seen in the intestinal tracts of flies expressing Duox^{dsRNA.Scer\UAS} under the control of Scer\GAL4^da.G32 is rescued by co-expression of Duox^Scer\UAS.cHa.

(Ha et al., 2005)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Cy^Scer\UAS.cHa

Duox^Scer\UAS.cHa

Duox^UAS.cHa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Ha

(Ha et al., 2005)

Secondary FlyBase IDs

References (9)

Report Sections

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