FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\drlΔintra.UAS.Tag:MYC
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General Information
Symbol
Dmel\drlΔintra.UAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0191173
Feature type
allele
Associated gene
Dmel\drl
Associated Insertion(s)
Carried in Construct
P{UAS-drl.Δintra.MYC}
Key Links
Transgenic product class
inframe_deletion
(Taillebourg et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Taillebourg et al., 2005)
Mutagen
in vitro construct
(Taillebourg et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-drl.Δintra.MYC}
Cytology
Description

UASt regulatory sequences drive expression of a 9.0kb PstI-SalI drl cDNA fragment ligated to a Tag:MYC tag. It encodes the first 295 amino acids of the drl protein linked to the Tag:MYC tag epitope by an isoleucine residue.

(Taillebourg et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
drl
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of drlΔintra.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4GH146 has no effect on dendrite targeting in the adult antennal lobe.

      (Wu et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Phenotype Manifest In
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of drlΔintra.Scer\UAS.T:Hsap\MYC does not suppress the distortion of the antennal lobe caused by expression of Wnt5Scer\UAS.cFa under the control of Scer\GAL4GH146.

      (Wu et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4repo.PU/drlΔintra.UAS.Tag:MYC partially rescues drl2

      (Yao et al., 2007)

      Scer\GAL4elav-C155/drlΔintra.UAS.Tag:MYC partially rescues drl2/drlR343

      (Taillebourg et al., 2005)
      Comments

      Expression of drlΔintra.Scer\UAS.T:Hsap\MYC in homozygous drlunspecified MARCM projection neuron clones induced in a drlunspecified/+ background fails to rescue the dendrite targeting defects of these clones.

      (Wu et al., 2014)

      Expression of drlΔintra.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4repo.PU partially rescues the antennal lobe defects of drl2 adults: both midline defects and targeting defects are partially rescued.

      (Yao et al., 2007)

      Expression of drlΔintra.Scer\UAS.T:Hsap\MYC, under the control of Scer\GAL4elav-C155 can completely rescue the mushroom body phenotype of drl2/drlR343 in 19% of cases.

      (Taillebourg et al., 2005)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      drlΔintra.Scer\UAS.T:Hsap\MYC
      drlΔintra.UAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (3)