FlyBase Allele Report: Dmel\dally[sec.UAS.Tag:MYC]

General Information

Symbol

Dmel\dally^{sec.UAS.Tag:MYC}

Species

D. melanogaster

Name

FlyBase ID

FBal0191644

Feature type

allele

Associated gene

Dmel\dally

Associated Insertion(s)

Carried in Construct

P{UAS-dally.sec}

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Takeo et al., 2005)

Progenitor genotype

Carried in construct

P{UAS-dally.sec}

Cytology

Description

UASt regulatory sequences replace the Hsp70 promoter sequences.

(Takeo et al., 2005)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dally

Tagged with

Tag:MYC

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

costal vein, with Scer\GAL4^A9

(Takeo et al., 2005)

larva, with Scer\GAL4^29BD

(Takeo et al., 2005)

mesothoracic tergum & chaeta | supernumerary, with Scer\GAL4^A9

(Takeo et al., 2005)

mesothoracic tergum & chaeta | supernumerary, with Scer\GAL4^hh-Gal4

(Takeo et al., 2005)

pupa, with Scer\GAL4^29BD

(Takeo et al., 2005)

wing, with Scer\GAL4^A9

(Takeo et al., 2005)

wing, with Scer\GAL4^dpp.blk1

(Takeo et al., 2005)

wing disc, with Scer\GAL4^29BD

(Takeo et al., 2005)

wing vein | ectopic, with Scer\GAL4^71B

(Takeo et al., 2005)

wing vein | ectopic, with Scer\GAL4^A9

(Takeo et al., 2005)

wing vein | ectopic, with Scer\GAL4^dpp.blk1

(Takeo et al., 2005)

wing vein | ectopic, with Scer\GAL4^en-e16E

(Takeo et al., 2005)

wing vein | ectopic, with Scer\GAL4^hh-Gal4

(Takeo et al., 2005)

Detailed Description

Statement

Reference

Expression of dally^{sec.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^C587 has no effect on germline stem cell number in the female germaria.

(Guo and Wang, 2009)

Ectopic expression of dally^{sec.Scer\UAS.T:Hsap\MYC} induces the phenotypes listed below, depending on the Scer\GAL4 driver. The percentages of animals showing each phenotype is given. Expression with the ubiquitous Scer\GAL4^29BD driver causes: giant larvae - 100%, giant pupae large imaginal wing discs. Expression in the wing and haltere discs with Scer\GAL4^A9 causes: defective eclosion - 43%, folded wings - 17%, wing overgrowth - 100%, enlargement of the costa in the wing hinge thick wing veins, mainly in the anterior - 100%, ectopic wing veins, mainly in the anterior - 100%, extra notal bristles - 78%. Expression in the wing pouch with Scer\GAL4^71B causes: thick wing veins, mainly in the anterior - 100%, ectopic wing veins, mainly in the anterior - 100%. Expression along the anterior-posterior compartment boundary with Scer\GAL4^dpp.blk1 causes: extra notal bristles - 60%, folded wings - 17%, thick wing veins - 100%, ectopic wing veins - 100%. Expression in the posterior compartment with Scer\GAL4^hh-Gal4 causes: thick wing veins, mainly in the anterior - 100%, ectopic wing veins, mainly in the anterior - 100%, extra notal bristles - 85%. Expression in the posterior compartment with Scer\GAL4^en-e16E causes: thick wing veins, mainly in the anterior - 100%, ectopic wing veins, mainly in the anterior - 100%. Expression of dally^{sec.Scer\UAS.T:Hsap\MYC}, under the control of Scer\GAL4^29BD, does not change the cell and tissue size of the salivary gland in third instar larvae.