FB2026_02 , released June 18, 2026
Allele: Dmel\cpa43D
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General Information
Symbol
Dmel\cpa43D
Species
D. melanogaster
Name
FlyBase ID
FBal0193691
Feature type
allele
Associated gene
Dmel\cpa
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Janody and Treisman, 2006)
Progenitor genotype
Cytology
Description

Amino acid replacement: N190G.

(Janody and Treisman, 2006)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      cpa43D has cell lethal phenotype, enhanceable by Scer\GAL4αTub84B.PL/vgUAS.cKa

      (Janody and Treisman, 2006)
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      cpa43D has wing disc | somatic clone phenotype, enhanceable by Scer\GAL4αTub84B.PL/vgUAS.cKa

      (Janody and Treisman, 2006)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of vgScer\UAS.cKa under the control of Scer\GAL4αTub84B.PL in cpa43D mutant clones leads to the extrusion of the clones from all regions of the wing disc, rather than from just the wing blade primordium.

      Adults expressing cpaScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4αTub84B.PL in a cpa43D/cpa69E or cpa43D/cpa107E background sometimes show wing, eye or bristle defects.

      (Janody and Treisman, 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      cpaKG02261

      (Janody and Treisman, 2006)
      Partially rescued by

      cpa43D/cpa107E is partially rescued by cpaUAS.Tag:HA/Scer\GAL4αTub84B.PL

      (Janody and Treisman, 2006)

      cpa69E/cpa43D is partially rescued by cpaUAS.Tag:HA/Scer\GAL4αTub84B.PL

      (Janody and Treisman, 2006)
      Comments

      Ubiquitous expression of cpaScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4αTub84B.PL rescues the lethality of cpa43D/cpa107E and cpa43D/cpa69E mutants, although some of the rescued adults exhibit wing, eye or bristle defects.

      (Janody and Treisman, 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      cpa43D
      (Janody and Treisman, 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)