FB2026_02 , released June 18, 2026
Allele: Dmel\bchs12
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General Information
Symbol
Dmel\bchs12
Species
D. melanogaster
Name
FlyBase ID
FBal0193791
Feature type
allele
Associated gene
Dmel\bchs
Associated Insertion(s)
P{EP}EP2299
Carried in Construct
Also Known As
EP(2L)2299, EP(2)2299
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Khodosh et al., 2006)
Mutagen
ethyl methanesulfonate
(Khodosh et al., 2006)
Progenitor genotype
bchsEP2299
(Khodosh et al., 2006)
Associated Insertion(s)
P{EP}EP2299
Cytology
Description

The progenitor P{EP}EP2299 insertion is still present on the chromosome.

(Khodosh et al., 2006)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      bchs12 mutants show no defects in the larval visual system or embryonic central nervous system.

      (Khodosh et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      bchs17/bchs12 is a suppressor | partially of lethal phenotype of Rab1193Bi/Rab11ex1

      (Khodosh et al., 2006)

      bchs17/bchs12 is a suppressor | partially of abnormal neuroanatomy phenotype of Rab1193Bi/Rab11ex1

      (Khodosh et al., 2006)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      bchs17/bchs12 is a suppressor of microchaeta phenotype of Rab1193Bi/Rab11ex1

      (Khodosh et al., 2006)

      bchs17/bchs12 is a suppressor | partially of posterior scutellar bristle phenotype of Rab1193Bi/Rab11ex1

      (Khodosh et al., 2006)

      bchs17/bchs12 is a suppressor | partially of bouton phenotype of Rab1193Bi/Rab11ex1

      (Khodosh et al., 2006)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The viability of Rab11ex1/Rab1193Bi is increased when flies are also mutant for bchs17/bchs12.

      The microchaeta loss of Rab11ex1/Rab1193Bi flies is completely suppressed by bchs17/bchs12. Further, posterior scutellar bristle length of Rab11ex1/Rab1193Bi flies is restored significantly by bchs17/bchs12.

      The bouton density and branching defects of Rab11ex1/Rab1193Bi larval NMJs at muscle 6/7 are significantly suppressed in bchs17/bchs12; Rab11ex1/Rab1193Bi double mutants.

      (Khodosh et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      P{EP}bchs12
      (FlyBase, 1992-)
      bchs12
      (Khodosh et al., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)