FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\rdx4
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General Information
Symbol
Dmel\rdx4
Species
D. melanogaster
Name
FlyBase ID
FBal0194659
Feature type
allele
Associated gene
Dmel\rdx
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Caused by aberration
    Df(3R)rdx4
    Cytology
    Description

    rdx4 is a complex rearrangement of the region upstream of exon 5, generated by imprecise excision of rdx1 insertion P{PZ}mei-P1903477.

    (Kent et al., 2006)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        rdx4 homozygotes hatch, but the sluggish, slow-growing larvae seldom survive beyond the first instar.

        Germline clones (lacking both maternal and zygotic rdx) of rdx4 yield embryos that develop and hatch normally.

        (Kent et al., 2006)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Fails to complement

        rdx1

        (Kent et al., 2006)
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        Comments
        Comments

        Based on embryonic and larval lethality, the following rdx alleles can be ranked from strongest to weakest as follows: rdx5 > rdx6 > rdx4 = rdx1.

        (Kent et al., 2006)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        rdx4
        (Kent et al., 2006)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)