FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\rdx1
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General Information
Symbol
Dmel\rdx1
Species
D. melanogaster
Name
FlyBase ID
FBal0184510
Feature type
allele
Associated gene
Dmel\rdx
Associated Insertion(s)
P{lacW}rdx1
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Kent et al., 2006)
Progenitor genotype
Associated Insertion(s)
P{lacW}rdx1
Cytology
Description

Insertion 33 nucleotides upstream of the start of exon 5.

(Kent et al., 2006)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      rdx1 homozygotes hatch, but the sluggish, slow-growing larvae seldom survive beyond the first instar.

      Germline clones (lacking both maternal and zygotic rdx) of rdx1 yield embryos that develop and hatch normally.

      (Kent et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      rdx1 is a suppressor of sex comb phenotype of Pc1

      (Strübbe et al., 2011)

      rdx1 is a suppressor of metathoracic leg phenotype of Pc1

      (Strübbe et al., 2011)

      rdx1 is a suppressor of mesothoracic leg phenotype of Pc1

      (Strübbe et al., 2011)

      rdx1 is a suppressor of sex comb phenotype of Pc3

      (Strübbe et al., 2011)

      rdx1 is a suppressor of metathoracic leg phenotype of Pc3

      (Strübbe et al., 2011)

      rdx1 is a suppressor of mesothoracic leg phenotype of Pc3

      (Strübbe et al., 2011)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Based on embryonic and larval lethality, the following rdx alleles can be ranked from strongest to weakest as follows: rdx5 > rdx6 > rdx4 = rdx1.

      (Kent et al., 2006)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Rdx1
      (Strübbe et al., 2011)
      rdx1
      (Bade et al., 2014, Baker et al., 2009, Kent et al., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)