Expression of α-CatGD8808 in follicle cells under the control of Scer\GAL4tj-NP1624 produces oogenesis defects. Ovarioles frequently form a single giant fused egg chamber that contains multiple germline cysts.
Follicle cell clones expressing α-CatGD8808 causes loss of adherens junctions and formation of α-Spec aggregates.
Adults expressing α-CatGD8808 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Depending on the insertion line used, expression under the control of Scer\GAL4Mef2.PR can result in viable flies or late pupal lethality.