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General Information
Symbol
Dmel\α-CatGD8808
Species
D. melanogaster
Name
FlyBase ID
FBal0198530
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Males expressing α-CatGD8808 under the control of Scer\GAL4Myo31DF-NP1548 sometimes show partial rotation of the genitalia.

Males expressing α-CatGD8808 under the control of Scer\GAL4Abd-B-LDN show partial rotation of the genitalia.

Expression of α-CatGD8808 in follicle cells under the control of Scer\GAL4tj-NP1624 produces oogenesis defects. Ovarioles frequently form a single giant fused egg chamber that contains multiple germline cysts.

Follicle cell clones expressing α-CatGD8808 causes loss of adherens junctions and formation of α-Spec aggregates.

Adults expressing α-CatGD8808 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

Depending on the insertion line used, expression under the control of Scer\GAL4Mef2.PR can result in viable flies or late pupal lethality.

External Data
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Other
Phenotype Manifest In
NOT Enhanced by
Statement
Reference
Other
Additional Comments
Genetic Interactions
Statement
Reference

Males co-expressing shgKK103334 and α-CatGD8808 under the control of Scer\GAL4Abd-B-LDN have defects in genital rotation, either showing partial (77%) or no (23%) rotation.

Co-expression of SCARGD11380 does not enhance the adherens junction phenotype seen in follicle cell clones expressing α-CatGD8808.

Co-expression of Arpc1KK108277 does not enhance the adherens junction phenotype seen in follicle cell clones expressing α-CatGD8808.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (3)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 1 )
Crossreferences
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
α-CatGD8808
Name Synonyms
Secondary FlyBase IDs
    References (10)