Expression of fwGD3327 under the control of Scer\GAL4sev.PU results in planar cell polarity defects in the eye, including altered ommatidial rotation and occasional symmetric ommatidia. Photoreceptor cell loss is also seen.
Expression of fwGD3327 under the control of Scer\GAL4pnr-MD237 results in orientation defects of bristles and cell hairs on the notum.
Expression of fwGD3327 under the control of Scer\GAL4en.PU results in defects in wing hair orientation.
Adults expressing fwGD3327 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.