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FB2026_01
,
released March 12, 2026
UASt regulatory sequences drive expression of an inverted repeat.
Expression of kayGD1469 RNAi under the control of Scer\GAL4pnr-MD237 does not significantly alter levels of pigmentation on the abdominal tergite 5 or 6 in adult females compared to controls.
Expression of kayGD1469 under the control of Scer\GAL4Bx-MS1096 results in male flies with weak wing size and patterning defects.
Expression of kayGD1469 under the control of Scer\GAL4Bx-MS1096 results in female flies with weak wing size and patterning defects.
Expression of kayGD1469 in C-I neurons under the control of Scer\GAL4221 results in ddaD neurons that have an increased number of dendritic branches compared to controls. The total dendritic length is increased in ddaE neurons.No defects are seen in vpda neurons.
Expression of kayGD1469 in C-IV neurons under the control of Scer\GAL4ppk.1.9 results in a reduction in total dendritic length in ddaC, v'ada and vdaB neurons. The total number of dendritic branches is also reduced in ddaC and v'ada neurons.
Flies expressing kayGD1469 under the control of Scer\GAL4P2.4.Pdf in the presence of Dcr-2Scer\UAS.cDa (which increases RNAi efficiency) under constant darkness conditions do not show a significant difference in locomotor activity period compared to controls.
Expression of kayGD1469 under the control of Scer\GAL4Hand.ΔVM.Switch (initiated by feeding flies RU486 during adulthood) decreases the frequency of arrhythmicity and improves the End-Diastolic Diameter (EDD) in old flies compared to controls.
Adults expressing kayGD1469 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Expression under the control of Scer\GAL4pnr-MD237 results in bristle morphology defects on the notum in 10-20% or 20-30% of the Scer\GAL4pnr-MD237 expression domain, depending on the insertion line used.
Expression under the control of Scer\GAL4pnr-MD237 results in planar polarity defects in the orientation of bristles of the notum in 40-50% or 80-90% of the Scer\GAL4pnr-MD237 expression domain, depending on the insertion line used.
Expression under the control of Scer\GAL4pnr-MD237 results in mild thorax closure defects.
Expression under the control of Scer\GAL4pnr-MD237 results in an enlarged notum.