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General Information
Symbol
Avic\GFPStat92E.10X
Species
A. victoria
Name
FlyBase ID
FBal0211029
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
10XSTAT92E-GFP, 10XSTAT-GFP, STAT92E-GFP, STAT-GFP, 10XSTAT::GFP, 10XSTAT-dGFP, 10xStatGFP
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Five tandem repeats of a 441bp genomic region from the first intron of Socs36E, which contains two potential Stat92E binding sites, are cloned upstream of a minimal heat shock promoter driving expression of EGFP.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
distribution deduced from reporter
Stage
Tissue/Position (including subcellular localization)
Reference
distribution deduced from reporter or direct label
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

Avic\GFPStat92E.10X is expressed in drpr and repo positive glial cells and is up-regulated in response to axotomy.

Avic\GFPStat92E.10X reporter activity is highly asymmetric within the anterior of the stage 14 large intestine. Cells on the inside of the hindgut curve show higher pathway activity than cells at comparable distances from the Upd-expressing large intestine on the outside of the curve. This difference in reporter activity is significant and not a consequence of increased cell density. Asymmetry in reporter activity is mirrored by expression of the endogenous JAK/STAT pathway target gene Socs36E.

In second instar larvae, reporter expression is observed throughout the disc proper. By early third instar, expression is repressed in the distal pouch and proximal notum,conincident with nub and eyg expression in these regions.

A subset of the dorsomedial neurosecretory cells labelled by Avic\GFPStat92E.10X also express Scer\GAL4VGAT.PF.

This GFP-reporter of JAK-STAT signaling is specifically expressed in the cells at the junction of the foregut and the midgut in third instar larvae.

Stat92E reporter is expressed in ISCs and enteroblasts.

 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Avic\GFPStat92E.10X
Name Synonyms
Secondary FlyBase IDs
    References (54)