UASt regulatory sequences drive expression of wild-type AMPKα.
long lived | RU486 conditional, with Scer\GAL4Mhc.Switch.PO
long lived | RU486 conditional, with Scer\GAL4Switch1.106
Expression of SNF1AWT.Scer\UAS under the control of either Scer\GAL4Mhc.Switch.PO or Scer\GAL4Switch1.106 during the adult stage (using RU486 to induce expression) increases longevity compared to controls.
Expression of AMPKαWT.Scer\UAS under the control of Scer\GAL4kirre.PU does not affect somatic muscle pattern in embryos. The size of the segmental border muscle and the DA1 muscle and the number of nuclei present in these muscles are normal.
AMPKαWT.UAS/Scer\GAL4Tub.PU rescues AMPKαD1