FlyBase Allele Report: Dmel\ab[UAS.S.cSa]

General Information

Symbol

Dmel\ab^UAS.S.cSa

Species

D. melanogaster

Name

FlyBase ID

FBal0215328

Feature type

allele

Associated gene

Dmel\ab

Associated Insertion(s)

Carried in Construct

P{UAS-ab.S}

Key Links

Transgenic product class

cDNA

(Sugimura et al., 2004)

wild_type

(Sugimura et al., 2004)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Sugimura et al., 2004)

wild_type

(Sugimura et al., 2004)

Mutagen

in vitro construct

(Sugimura et al., 2004)

Progenitor genotype

Carried in construct

P{UAS-ab.S}

Cytology

Description

UASt regulatory sequences drive expression of the shorter isoform of ab, corresponding to clone RE25924.

(Sugimura et al., 2004)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Scer\GAL4^109(2)80, Scer\GAL4^IG1-2

(Sugimura et al., 2004)

Phenotype Manifest In

larval dorsal multidendritic neuron ddaA, with Scer\GAL4^109(2)80, Scer\GAL4^IG1-2

(Sugimura et al., 2004)

Detailed Description

Statement

Reference

Expression of ab^{Scer\UAS.S.cSa}, under the control of Scer\GAL4^109(2)80 and Scer\GAL4^IG1-2, results in a reduction in dendritic field size and terminal number of ddA neurons.

(Sugimura et al., 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^109(2)80/ab^UAS.S.cSa, Scer\GAL4^IG1-2 is a suppressor | partially of abnormal neuroanatomy phenotype of Scer\GAL4^109(2)80, Scer\GAL4^IG1-2, ct^UAS.cPa

(Sugimura et al., 2004)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^109(2)80, Scer\GAL4^IG1-2, ab^UAS.S.cSa has larval dorsal multidendritic neuron ddaA phenotype, suppressible by Scer\GAL4^109(2)80/ct^UAS.cPa, Scer\GAL4^IG1-2

(Sugimura et al., 2004)

Suppressor of

Statement

Reference

Scer\GAL4^109(2)80/ab^UAS.S.cSa, Scer\GAL4^IG1-2 is a suppressor | partially of larval dorsal multidendritic neuron ddaE phenotype of Scer\GAL4^109(2)80, Scer\GAL4^IG1-2, ct^UAS.cPa

(Sugimura et al., 2004)

Additional Comments

Genetic Interactions

Statement

Reference

Coexpression of ct^Scer\UAS.cPa with ab^{Scer\UAS.S.cSa}, under the control of Scer\GAL4^109(2)80 and Scer\GAL4^IG1-2, partially suppresses the reduction of dendritic field size and terminal number of ddA neurons seen when ab^{Scer\UAS.L.cSa} is expressed alone. This coexpression also leads to a partial suppression of the dendritic overgrowth and overbranching of ddaE neurons, seen when ct^Scer\UAS.cPa is expressed under the control of Scer\GAL4^109(2)80 and Scer\GAL4^IG1-2.

(Sugimura et al., 2004)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

ab^UAS.S.cSa/Scer\GAL4^pk-IG1-1 rescues ab^k02807/ab^clu-1

(Sugimura et al., 2004)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

ab^{Scer\UAS.S.cSa}

ab^UAS.S.cSa

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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