Lesion in the prom gene.
Mutation affects the donor site.
Nucleotide substitution: G1226A.
The external morphology of the eye is indistinguishable from wild type in mutant animals. Mutant rhabdomeres are fragmented and rhabdomeres are joined to each other and to stalks of other photoreceptors by inappropriate adhesions. prom2 photoreceptors are indistinguishable from wild type at 37% pupal development (p.d.). The mutant phenotype is clearly seen by 55% p.d. The inter-rhabdomeral space fails to open and photoreceptor cells contact each other in both rhabdomere tip-to-tip and rhabdomere-to-stalk contacts. Distinctive stalk and rhabdomere membranes are evident, but they are irregularly ordered. Loops of stalk membrane are trapped by abnormal adhesions. Contacts between photoreceptor cells seen in adult ommatidia commonly include those seen during rhabdomere extension; the rhabdomere of R4 often bifurcates to contact R2 and R7. In addition, strong R5/R6 contact (not seen during extension) is also common in mutant adults.
The external morphology of the eye is indistinguishable from wild type in mutant animals. Mutant rhabdomeres are fragmented and rhabdomeres are joined to each other and to stalks of other photoreceptors by inappropriate adhesions. eyc1 photoreceptors are indistinguishable from wild type at 37% pupal development (p.d.). The mutant phenotype is clearly seen by 55% p.d. The inter-rhabdomeral space fails to open and photoreceptor cells contact each other in both rhabdomere tip-to-tip and rhabdomere-to-stalk contacts. Distinctive stalk and rhabdomere membranes are evident, but they are irregularly ordered. Loops of stalk membrane are trapped by abnormal adhesions. Contacts between photoreceptor cells seen in adult ommatidia commonly include those seen during rhabdomere extension; the rhabdomere of R4 often bifurcates to contact R2 and R7. In addition, strong R5/R6 contact (not seen during extension) is also common in mutant adults.
Separable from: Actn4.
FlyBase curator comment: The prom2 allele was previously referred to as "eyc2" in FlyBase due to confusion over which transcription unit corresponds to the "eyc" complementation group. However, FBrf0198649 shows that the lesion in the mutant maps within the prom transcription unit, and thus the allele is now listed as an allele of prom in FlyBase.