FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Hsc70-4e19
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General Information
Symbol
Dmel\Hsc70-4e19
Species
D. melanogaster
Name
FlyBase ID
FBal0217430
Feature type
allele
Associated gene
Dmel\Hsc70-4
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Hennig et al., 2006)
Progenitor genotype
Cytology
Description

Amino acid replacement: R301C.

(Hennig et al., 2006)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:15,245,260..15,245,260 [+]
Nucleotide change:

C15245260T

Amino acid change:

R301C | Hsc70-4-PA; R301C | Hsc70-4-PB; R301C | Hsc70-4-PC; R301C | Hsc70-4-PD; R301C | Hsc70-4-PE; R301C | Hsc70-4-PF; R301C | Hsc70-4-PG

Reported amino acid change:

R301C

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Hennig et al., 2006)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Hsc70-4e19/Hsc70-4[+], mTorey.Tag:FLAG has eye phenotype, suppressible by Hsc70-4+t14

      (Hennig et al., 2006)
      Enhancer of
      Statement
      Reference

      Hsc70-4e19/Hsc70-4[+] is an enhancer of eye phenotype of mTorey.Tag:FLAG

      (Hennig et al., 2006)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Heterozygous Hsc70-4e19 mutants cause a further reduction in eye size of Torey.hs.T:Zzzz\FLAG mutants.

      (Hennig et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Hsc70-4e19 is rescued by Hsc70-4+t14

      (Hennig et al., 2006)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Hsc70-4e19
      (Hennig et al., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)