FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\parkUAS.cMa
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General Information
Symbol
Dmel\parkUAS.cMa
Species
D. melanogaster
Name
FlyBase ID
FBal0217549
Feature type
allele
Associated gene
Dmel\park
Associated Insertion(s)
Carried in Construct
P{UAS-park.cMa}
Key Links
Transgenic product class
cDNA
(Muñoz-Soriano and Paricio, 2007)
wild_type
(Muñoz-Soriano and Paricio, 2007)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Muñoz-Soriano and Paricio, 2007)
wild_type
(Muñoz-Soriano and Paricio, 2007)
Mutagen
in vitro construct
(Muñoz-Soriano and Paricio, 2007)
Progenitor genotype
Carried in construct
P{UAS-park.cMa}
Cytology
Description

UASt regulatory sequences drive expression of the SD01679 park cDNA.

(Muñoz-Soriano and Paricio, 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
park
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  neurodegenerative disease
      modeled by Septin4UAS.cMa
      (Muñoz-Soriano and Paricio, 2007)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      parkUAS.cMa/Scer\GAL4Ddc.PL is a suppressor | partially of dopaminergic neuron & adult brain phenotype of Scer\GAL4Ddc.PL, Septin4UAS.cMa

      (Muñoz-Soriano and Paricio, 2007)

      Scer\GAL4ple.PF/parkUAS.cMa is a suppressor | partially of dopaminergic neuron & adult brain phenotype of Scer\GAL4ple.PF, Septin4UAS.cMa

      (Muñoz-Soriano and Paricio, 2007)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The reduction in the number of dopaminergic neurons in the dorsomedial clusters of 40-day old adult brains caused by expression of Sep4Scer\UAS.cMa under the control of Scer\GAL4Ddc.PL or Scer\GAL4ple.PF is almost restored back to control levels when of parkScer\UAS.cMa is coexpressed.

      (Muñoz-Soriano and Paricio, 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      parkScer\UAS.cMa
      parkUAS.cMa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)