FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Pkd2MB06703
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General Information
Symbol
Dmel\Pkd2MB06703
Species
D. melanogaster
Name
FlyBase ID
FBal0217633
Feature type
allele
Associated gene
Dmel\Pkd2
Associated Insertion(s)
Mi{ET1}Pkd2MB06703
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    Mi{ET1}Pkd2MB06703
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    Mi{ET1}
    Encoded product / tool
    GAL4
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        In contrast to wild type, the number of Pkd2ko67 / Pkd2MB06703 sperm that enter the distal seminal receptacle (DSR) vary greatly on an individual basis and the average number of sperm stored per female per mating is only 5.5. Only 4.4 F1 progeny are produced per female from matings to these mutant males.

        (Yang et al., 2011)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Sperm from lobolobo/loboMB00722; Pkd2ko67 / Pkd2MB06703 double mutants are motile, are produced in large numbers and can enter the uterus as normal. However, in contrast to wild type, the number of sperm that enter the distal seminal receptacle (DSR) vary greatly on an individual basis and the average number of sperm stored per female per mating is only 2.4. Only 2.9 F1 progeny are produced per female from matings to these double-mutant males.

        Stored sperm from lobolobo/loboMB00722; Pkd2ko67 / Pkd2MB06703 double mutant males can exit the distal seminal receptacle and fertilize the egg.

        (Yang et al., 2011)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        Pkd2MB06703
        (Yang et al., 2011, Bellen, 2008.6.30)
        Pkd2MB0670
        (Turner et al., 2016)
        Name Synonyms
        Secondary FlyBase IDs
          References (3)