FlyBase Allele Report: Dmel\Wnk[MB06499]

General Information

Symbol

Dmel\Wnk^MB06499

Species

D. melanogaster

Name

FlyBase ID

FBal0218756

Feature type

allele

Associated gene

Dmel\Wnk

Associated Insertion(s)

Mi{ET1}Wnk^MB06499

Carried in Construct

Also Known As

wnk^MB

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

Mi{ET1}Wnk^MB06499

Cytology

Description

Allele components

Component

Use(s)

Inserted element

Mi{ET1}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:21,551,838..21,551,838 [+]

(Bellen, 2008.11.7)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal

(Yarikipati et al., 2023, Serysheva et al., 2013)

lethal (with Df(3L)ED4978)

(Yarikipati et al., 2023, Serysheva et al., 2013)

lethal (with Wnk^AA16.DsRed+)

(Yarikipati et al., 2023)

lethal (with Wnk^ex22)

(Yarikipati et al., 2023, Serysheva et al., 2013)

viable (with Wnk^AA16)

(Yarikipati et al., 2023)

viable (with Wnk^AA21)

(Yarikipati et al., 2023)

Phenotype Manifest In

posterior wing margin | somatic clone

(Serysheva et al., 2013)

wing margin bristle | somatic clone

(Serysheva et al., 2013)

Detailed Description

Statement

Reference

Mutant clones in the wing result in loss of wing margin and missing margin bristles. However, no typical planar cell polarity phenotypes are detected.

(Serysheva et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Suppressor of

Statement

Reference

Wnk[+]/Wnk^MB06499 is a non-suppressor of abnormal planar polarity phenotype of dsh^sev.PU

(Serysheva et al., 2013)

Phenotype Manifest In

Suppressor of

Statement

Reference

Wnk[+]/Wnk^MB06499 is a suppressor of eye photoreceptor cell phenotype of dsh^sev.PU

(Serysheva et al., 2013)

Additional Comments

Genetic Interactions

Statement

Reference

Wnk^MB06499/+ suppresses the loss of photoreceptor phenotype but not the planar cell polarity phenotype of dsh^sev.PU eyes.

(Serysheva et al., 2013)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Df(3L)ED4978/Wnk^MB06499 is rescued by Wnk^{ΔMid.αTub84B.Tag:HA}

(Yarikipati et al., 2023)

Df(3L)ED4978/Wnk^MB06499 is rescued by Wnk^{αTub84B.Tag:HA}

(Yarikipati et al., 2023)

Wnk^AA16.DsRed+/Wnk^MB06499 is rescued by Wnk^{ΔCC.αTub84B.Tag:HA}

(Yarikipati et al., 2023)

Wnk^AA16.DsRed+/Wnk^MB06499 is rescued by Wnk^{ΔCC2.αTub84B.Tag:HA}

(Yarikipati et al., 2023)

Wnk^AA16.DsRed+/Wnk^MB06499 is rescued by Wnk^{ΔMid.αTub84B.Tag:HA}

(Yarikipati et al., 2023)

Wnk^AA16.DsRed+/Wnk^MB06499 is rescued by Wnk^{αTub84B.Tag:HA}

(Yarikipati et al., 2023)

Wnk^MB06499 is rescued by Wnk^tub.Tag:HA

(Serysheva et al., 2013)

Partially rescued by

Wnk^AA16.DsRed+/Wnk^MB06499 is partially rescued by Wnk^{ΔAI.αTub84B.Tag:HA}

(Yarikipati et al., 2023)

Not rescued by

Df(3L)ED4978/Wnk^MB06499 is not rescued by Wnk^{ΔAI.αTub84B.Tag:HA}

(Yarikipati et al., 2023)

Df(3L)ED4978/Wnk^MB06499 is not rescued by Wnk^{ΔCC.αTub84B.Tag:HA}

(Yarikipati et al., 2023)

Df(3L)ED4978/Wnk^MB06499 is not rescued by Wnk^{ΔCC1.αTub84B.Tag:HA}

(Yarikipati et al., 2023)

Df(3L)ED4978/Wnk^MB06499 is not rescued by Wnk^{ΔCC2.αTub84B.Tag:HA}

(Yarikipati et al., 2023)

Df(3L)ED4978/Wnk^MB06499 is not rescued by Wnk^{ΔCT.αTub84B.Tag:HA}

(Yarikipati et al., 2023)

Df(3L)ED4978/Wnk^MB06499 is not rescued by Wnk^{ΔNT.αTub84B.Tag:HA}

(Yarikipati et al., 2023)

Wnk^AA16.DsRed+/Wnk^MB06499 is not rescued by Wnk^{ΔCC1.αTub84B.Tag:HA}

(Yarikipati et al., 2023)

Wnk^AA16.DsRed+/Wnk^MB06499 is not rescued by Wnk^{ΔCT.αTub84B.Tag:HA}

(Yarikipati et al., 2023)

Wnk^AA16.DsRed+/Wnk^MB06499 is not rescued by Wnk^{ΔNT.αTub84B.Tag:HA}

(Yarikipati et al., 2023)

Comments

Wnk^{tub.T:Ivir\HA1} fully rescues the lethality caused by Wnk^MB06499.

(Serysheva et al., 2013)

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

26050

w¹¹¹⁸; Mi{ET1}Wnk^MB06499/TM6C, Sb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

CG7177^MB06499

(Bellen, 2008.11.7)

Wnk^MB06499

(Yarikipati et al., 2023)

Wnk^MB

(Yarikipati et al., 2023)

wnk^MB06499

(Serysheva et al., 2013, Serysheva et al., 2013)

wnk^MB

(Serysheva et al., 2013)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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