FB2026_02 , released June 18, 2026
Allele: Dmel\nkdΔR1SΔ30aaNLS.UAS.Tag:NLS(SV40-largeT),EGFP
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General Information
Symbol
Dmel\nkdΔR1SΔ30aaNLS.UAS.Tag:NLS(SV40-largeT),EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0219567
Feature type
allele
Associated gene
Dmel\nkd
Associated Insertion(s)
Carried in Construct
P{UAS-nkd.ΔR1SΔ30aaNLS.GFPC}
Key Links
Transgenic product class
inframe_deletion
(Chan et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Chan et al., 2008)
Mutagen
in vitro construct
(Chan et al., 2008)
Progenitor genotype
Carried in construct
P{UAS-nkd.ΔR1SΔ30aaNLS.GFPC}
Cytology
Description

UAS regulatory sequences drive expression of an internally deleted form of nkd (amino acids 179-370 and 543-572 are missing) which is tagged at the C-terminal end with EGFP. In addition, a nuclear localization signal (Tag:NLS(SV40-largeT)) has been inserted at the site where amino acids 543-572 have been deleted.

(Chan et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
nkd
Tagged with
EGFP
Tag:NLS(SV40-largeT)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Scer\GAL4da.G32/nkdΔR1SΔ30aaNLS.UAS.Tag:NLS(SV40-largeT),EGFP fails to rescue nkd3

      (Chan et al., 2008)
      Comments

      Expression of nkdΔR1SΔ30aaNLS.Scer\UAS.T:SV40\nls2,T:Avic\GFP-EGFP under the control of Scer\GAL4da.G32 does not rescue the nkd3 embryonic cuticle phenotype.

      (Chan et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      NkdΔR1SΔ30aaNLS/GFPC
      (Chan et al., 2008)
      nkdΔR1SΔ30aaNLS.Scer\UAS.T:SV40\nls-largeT,T:Avic\GFP-EGFP
      nkdΔR1SΔ30aaNLS.Scer\UAS.T:SV40\nls2,T:Avic\GFP-EGFP
      nkdΔR1SΔ30aaNLS.UAS.Tag:NLS(SV40-largeT),EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (2)