FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Scer\GAL4Tsp42Ef-GSG5255
Open Close
General Information
Symbol
Scer\GAL4Tsp42Ef-GSG5255
Species
S. cerevisiae
Name
FlyBase ID
FBal0220200
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
P{Switch2}Tsp42EfGSG5255
Carried in Construct
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{Switch2}Tsp42EfGSG5255
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{Switch2}
    Encoded product / tool
    GAL4::GS
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        distribution deduced from reporter (Gal4 UAS)
        Stage
        Tissue/Position (including subcellular localization)
        Reference
        third instar larval stage
        larval neuron | subset of larval ventral nerve cord
        (Nicholson et al., 2008)
        tendon cell
        (Nicholson et al., 2008)
        sensory neuron of embryonic/larval antennal lobe
        (Nicholson et al., 2008)
        larval neuron | subset of larval brain
        (Nicholson et al., 2008)
        embryonic/larval neuromuscular junction
        (Nicholson et al., 2008)
        Additional Information
        Statement
        Reference

        ScerGAL4Tsp42Ef-GSG5255 drives mifepristone-inducible expression primarily neuronally. Strong expression is observed in the ventral nerve cord in 4-5 cells per hemisegment at dorsal midline (no A1-7 dorsal motor neurons), ~15+ cells per hemisegment in lateral clusters, and 15+ ventral cells per hemisegment. Strong sensory expression is observed in the antennal lobes, and weak expression in a few scattered cells in the brain, including ~3-5 cells with interhemisphere processes. Strong expression is observed in type Ib boutons of neuromuscular junctions of most but not all muscles; no expression in muscles 4, 6 or 7. Expression is also observed in muscle attachment cells.

        (Nicholson et al., 2008)
         
        Marker for
        Reflects expression of
        Tsp42Ef
        (Nicholson et al., 2008)
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Scer\GAL4Tsp42Ef-GSG5255
        Name Synonyms
        Secondary FlyBase IDs
          References (2)