FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\BHDUAS.cSa
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General Information
Symbol
Dmel\BHDUAS.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Singh
FlyBase ID
FBal0221542
Feature type
allele
Associated gene
Dmel\BHD
Associated Insertion(s)
Carried in Construct
P{UAS-BHD.S}
Key Links
Transgenic product class
cDNA
(Singh et al., 2006)
wild_type
(Singh et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Singh et al., 2006)
wild_type
(Singh et al., 2006)
Mutagen
in vitro construct
(Singh et al., 2006)
Progenitor genotype
Carried in construct
P{UAS-BHD.S}
Cytology
Description

UASt regulatory sequences drive expression of a BHD cDNA.

(Singh et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
BHD
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of BHDScer\UAS.cSa under the control of Scer\GAL4nos.PG does not significantly affect the number of germline stem cells in the testis.

      (Singh et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Scer\GAL4nanos.PG/BHDUAS.cSa is a suppressor | partially of spermatogonium | heat sensitive phenotype of Stat92EF/Stat92Ej6C8

      (Singh et al., 2006)

      Scer\GAL4nanos.PG/BHDUAS.cSa is a suppressor | partially of male germline stem cell | heat sensitive phenotype of Stat92EF/Stat92Ej6C8

      (Singh et al., 2006)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of BHDScer\UAS.cSa under the control of Scer\GAL4nos.PG significantly slows down the loss of germ cell phenotype that is seen in Stat92EF/Stat92Ej6C8 testes at 29[o]C. After 4 days at 29[o]C, 26% of the double mutant testes contain one or more germline stem cells and most of the testes retain spermatogonia. After 7 days at 29[o]C, 8% of the double mutant testes have one or more germline stem cells and 64% retain spermatogonia.

      (Singh et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      BHDScer\UAS.cSa
      BHDUAS.cSa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Singh
      Secondary FlyBase IDs
        References (1)