FlyBase Allele Report: Dmel\Dop1R1[KK102341]

General Information

Symbol

Dmel\Dop1R1^KK102341

Species

D. melanogaster

Name

FlyBase ID

FBal0231733

Feature type

allele

Associated gene

Dmel\Dop1R1

Associated Insertion(s)

Carried in Construct

P{KK102341}

Also Known As

UAS-Dop1R1-RNAi, UAS-Dop1R1^RNAi, UAS-DopR1-IR, UAS-dDA1^RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK102341}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK102341

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal chemosensory behavior | larval stage, with Scer\GAL4^NPF.1

(Pu et al., 2018)

abnormal courtship behavior | male, with Scer\GAL4¹⁴⁷¹

(Keleman et al., 2012)

abnormal courtship behavior | male, with Scer\GAL4^Tab2-201Y

(Keleman et al., 2012)

abnormal feeding behavior | larval stage, with Scer\GAL4^NPF.1

(Pu et al., 2018)

abnormal learning | male, with Scer\GAL4¹⁴⁷¹

(Keleman et al., 2012)

abnormal learning | male, with Scer\GAL4^Tab2-201Y

(Keleman et al., 2012)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of Dop1R1^KK102341 under the control of Scer\GAL4^NPF.1 in larvae causes a shift in odor-induced increases in mouth hook contractions towards higher concentrations of odorants, compared to controls.

(Pu et al., 2018)

Expression of Dop1R1^KK102341 driven by Scer\GAL4^GMR23E10 does not significantly affect sleep amount per day, compared to controls.

(Pimentel et al., 2016)

Expression of Dop1R1^KK102341 under the control of Scer\GAL4^dimm-929 does not affect sensitivity to (S,Z,Z)-CH503 (a more potent stereoisomer of the gustatory sex pheromone CH503). As in wild type flies, courtship defects are seen in response to (S,Z,Z)-CH503.

(Shankar et al., 2015)

Males expressing DopR^KK102341 under the control of either Scer\GAL4^Tab2-201Y or Scer\GAL4¹⁴⁷¹ show significantly impaired courtship learning compared to controls.

Males expressing DopR^KK102341 under the control of either Scer\GAL4^c739 or Scer\GAL4^c305a show normal courtship learning.

(Keleman et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Dop1R1^KK102341, Scer\GAL4^NPF.PU is a non-enhancer of abnormal feeding behavior | larval stage | heat sensitive phenotype of Scer\GAL4^NPF.PU, TrpA1^UAS.(B).cKa

(Pu et al., 2018)

NOT Suppressor of

Statement

Reference

Dop1R1^KK102341, Scer\GAL4^NPF.PU is a non-suppressor of abnormal feeding behavior | larval stage | heat sensitive phenotype of Scer\GAL4^NPF.PU, TrpA1^UAS.(B).cKa

(Pu et al., 2018)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v107058

P{KK102341}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Dop1R1^KK102341

Dop1R1^RNAi

(Frighetto et al., 2022)

DopR^KK102341

Name Synonyms

Secondary FlyBase IDs

References (25)

Report Sections

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