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General Information
Symbol
Dmel\armKK102545
Species
D. melanogaster
Name
FlyBase ID
FBal0231853
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
arm RNAi, Arm-RNAi
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expressing armKK102545 under the control of Scer\GAL4GMR.PU leads to a necrotic, very rough eye phenotype.

Scer\GAL4tj-NP1624-mediated expression abolishes cyst encapsulation and results in germline cysts completely lacking an epithelium. Affected ovarioles look like tubes in which naked cysts pile up.

armKK102545/+; Scer\GAL4Mef2.247.Switch/+ flies fed on RU486-containing food exhibit impaired long-term memory, tested at 24 hours after 5X spaced training, whereas the 24 hour memory after 5X massed training or 3 minute memory after 1X training is not significantly different from that determined in unfed flies of the same genotype. Silencing arm expression in the adult mushroom bodies produces a specific deficit in protein-synthesis-dependent long-term memory. Flies withdrawn from RU486-containing food for 5 days regain a 24 hour long-term memory performance that is indistinguishable from that of the no-RU group.

Flies with induced expression of armKK102545 in the adult mushroom bodies (under the control of Scer\GAL4Mef2.247.Switch) exhibit a significant decrease in 24 hour long-term memory after 5X spaced training using benzaldehyde as the conditioned stimulus paired, compared with flies of the same genotype that were uninduced.

When armKK102545 is expressed in dorsal cluster neurons under the control of Scer\GAL4ato.3.6 has no effect on the branching pattern in the adult medulla is disturbed.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Co-expression of armS2.Scer\UAS.T:Hsap\MYC rescues the long term memory of RU486-fed armGD1372/+; Scer\GAL4Mef2.247.Switch/+ flies.

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (14)