FlyBase Allele Report: Dmel\Adar[JF02942]

General Information

Symbol

Dmel\Adar^JF02942

Species

D. melanogaster

Name

FlyBase ID

FBal0239447

Feature type

allele

Associated gene

Dmel\Adar

Associated Insertion(s)

Carried in Construct

P{TRiP.JF02942}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

(Perkins et al., 2009)

Progenitor genotype

Carried in construct

P{TRiP.JF02942}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-JF02942

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal flight | adult stage, with Scer\GAL4^elav-C155

(Varte et al., 2022)

decreased cell number | oogenesis, with Scer\GAL4^nanos.PU

(Sun et al., 2023)

decreased fecundity, with Scer\GAL4^{VP16.nanos.UTR}

(Zhang et al., 2024)

increased cell number | spermatogenesis, with Scer\GAL4^{VP16.nanos.UTR}

(Zhang et al., 2024)

increased occurrence of cell division | spermatogenesis, with Scer\GAL4^{VP16.nanos.UTR}

(Zhang et al., 2024)

Phenotype Manifest In

female germline stem cell | decreased number, with Scer\GAL4^nanos.PU

(Sun et al., 2023)

male germline stem cell | increased number, with Scer\GAL4^{VP16.nanos.UTR}

(Zhang et al., 2024)

Detailed Description

Statement

Reference

Expression of Adar^JF02942 in muscle under the control of Scer\GAL4^Mef2.PU results in significant hyperglycaemia.

(Ugrankar et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Adar^JF02942, Scer\GAL4^{VP16.nanos.UTR} has increased cell number | spermatogenesis phenotype, suppressible by tkv^GD2549, Scer\GAL4^{VP16.nanos.UTR}

(Zhang et al., 2024)

Phenotype Manifest In

Suppressed by

Statement

Reference

Adar^JF02942, Scer\GAL4^{VP16.nanos.UTR} has male germline stem cell | increased number phenotype, suppressible by tkv^GD2549, Scer\GAL4^{VP16.nanos.UTR}

(Zhang et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

28311

y¹ v¹; P{TRiP.JF02942}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Adar^JF02942

adar^JF02942

(Bernstein et al., 2016)

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

Open Close