FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\shiFL54
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General Information
Symbol
Dmel\shiFL54
Species
D. melanogaster
Name
FlyBase ID
FBal0240371
Feature type
allele
Associated gene
Dmel\shi
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Windler and Bilder, 2010)
Mutagen
ethyl methanesulfonate
(Yan et al., 2009)
Progenitor genotype
Cytology
Description

A deletion at codon 102, resulting in a frame-shift that induces a premature stop codon within the GTPase binding domain.

(Windler and Bilder, 2010)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous mutant imaginal discs show neoplastic phenotypes.

      (Windler and Bilder, 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      shiFL54 does not suppress the photoreceptor loss seen in Vps43B1 mutant eye disc clones (in which cell death has been prevented using DroncI29).

      (Legent et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      shiFL54
      (Legent et al., 2015, de Vreede et al., 2014, Johnson et al., 2012, Windler and Bilder, 2010, Yan et al., 2009)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)