FlyBase Allele Report: Dmel\Rho1[RNAi.2.UAS]

General Information

Symbol

Dmel\Rho1^RNAi.2.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0240535

Feature type

allele

Associated gene

Dmel\Rho1

Associated Insertion(s)

Carried in Construct

P{UAS-Rho1.RNAi.2}

Key Links

Transgenic product class

RNAi_reagent

(Warner and Longmore, 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Warner and Longmore, 2009)

Mutagen

in vitro construct

(Warner and Longmore, 2009)

Progenitor genotype

Carried in construct

P{UAS-Rho1.RNAi.2}

Cytology

Description

UAS regulatory regions drive expression of Rho1 inverted repeat coding sequences corresponding to bases 770-1310.

(Warner and Longmore, 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Rho1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates high grade glioma

modeled by Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, btl::Egfr^λ.UAS

(Chen et al., 2019)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

partially lethal - majority die, with Scer\GAL4^repo.PU

(Chen et al., 2019)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Rho1^RNAi.2.UAS/Hsap\RELA^AD.VT028327, Scer\GAL4^DBD.R22E04 is a non-enhancer of abnormal neuroanatomy | adult stage phenotype of Hsap\RELA^AD.VT028327, Scer\GAL4^DBD.R22E04, Ten-m^UAS.Tag:V5

(Xu et al., 2024)

Suppressor of

Statement

Reference

Rho1^RNAi.2.UAS, Scer\GAL4^repo.PU is a suppressor of abnormal neuroanatomy | third instar larval stage phenotype of Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, Scer\GAL4^repo.PU, btl::Egfr^λ.UAS

(Chen et al., 2019)

Rho1^RNAi.2.UAS, Scer\GAL4^repo.PU is a suppressor of neoplasia | third instar larval stage phenotype of Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, Scer\GAL4^repo.PU, btl::Egfr^λ.UAS

(Chen et al., 2019)

NOT Suppressor of

Statement

Reference

Rho1^RNAi.2.UAS/Hsap\RELA^AD.VT028327, Scer\GAL4^DBD.R22E04 is a non-suppressor of abnormal neuroanatomy | adult stage phenotype of Hsap\RELA^AD.VT028327, Scer\GAL4^DBD.R22E04, Ten-m^UAS.Tag:V5

(Xu et al., 2024)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Rho1^RNAi.2.UAS/Hsap\RELA^AD.VT028327, Scer\GAL4^DBD.R22E04 is a non-enhancer of adult antennal lobe phenotype of Hsap\RELA^AD.VT028327, Scer\GAL4^DBD.R22E04, Ten-m^UAS.Tag:V5

(Xu et al., 2024)

Rho1^RNAi.2.UAS/Hsap\RELA^AD.VT028327, Scer\GAL4^DBD.R22E04 is a non-enhancer of neuron projection | adult stage phenotype of Hsap\RELA^AD.VT028327, Scer\GAL4^DBD.R22E04, Ten-m^UAS.Tag:V5

(Xu et al., 2024)

Suppressor of

Statement

Reference

Rho1^RNAi.2.UAS, Scer\GAL4^repo.PU is a suppressor of larval brain | third instar larval stage phenotype of Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, Scer\GAL4^repo.PU, btl::Egfr^λ.UAS

(Chen et al., 2019)

Rho1^RNAi.2.UAS, Scer\GAL4^repo.PU is a suppressor of larval brain neuropil glial cell | third instar larval stage phenotype of Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, Scer\GAL4^repo.PU, btl::Egfr^λ.UAS

(Chen et al., 2019)

NOT Suppressor of

Statement

Reference

Rho1^RNAi.2.UAS/Hsap\RELA^AD.VT028327, Scer\GAL4^DBD.R22E04 is a non-suppressor of adult antennal lobe phenotype of Hsap\RELA^AD.VT028327, Scer\GAL4^DBD.R22E04, Ten-m^UAS.Tag:V5

(Xu et al., 2024)

Rho1^RNAi.2.UAS/Hsap\RELA^AD.VT028327, Scer\GAL4^DBD.R22E04 is a non-suppressor of neuron projection | adult stage phenotype of Hsap\RELA^AD.VT028327, Scer\GAL4^DBD.R22E04, Ten-m^UAS.Tag:V5

(Xu et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

29003

w^*; P{UAS-Rho1.RNAi.2}2/CyO

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Rho1^{2.dsRNA.Scer\UAS}

Rho1^RNAi.2.UAS

Rho1^{dsRNA.2.Scer\UAS}

Rho1^dsRNA.2.UAS

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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