FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\rdgAUAS.cRa
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General Information
Symbol
Dmel\rdgAUAS.cRa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Raghu
FlyBase ID
FBal0241091
Feature type
allele
Associated gene
Dmel\rdgA
Associated Insertion(s)
Carried in Construct
P{UAS-rgdA.R}
Key Links
Transgenic product class
wild_type
(Raghu et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Raghu et al., 2009)
Mutagen
in vitro construct
(Raghu et al., 2009)
Progenitor genotype
Carried in construct
P{UAS-rgdA.R}
Cytology
Description

UAS regulatory sequences drive expression of rdgA.

(Raghu et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
rdgA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Retinal extracts of flies expressing rdgAScer\UAS.cRa under the control of Scer\GAL4GMR.PF show a significant elevation of a single species of phosphatidic acid (predicted fatty acyl composition 16:0 / 18:2 ) compared to controls. The levels of phosphatidylcholine, diacylglycerol and phosphatidylinositol in the retinal extracts are normal.

      Expression of rdgAScer\UAS.cRa under the control of Scer\GAL4GMR.PF results in accumulation of membraneous and vesicular transport intermediates in the cell body of the photoreceptor cells.

      (Raghu et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Suppressor of
      Statement
      Reference

      Scer\GAL4ninaE.PU/rdgAUAS.cRa is a suppressor of retina | adult stage | progressive | conditional phenotype of Pld3.1

      (Thakur et al., 2016)

      Scer\GAL4ninaE.PU/rdgAUAS.cRa is a suppressor of ommatidium | adult stage | progressive | conditional phenotype of Pld3.1

      (Thakur et al., 2016)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The light-dependent retinal degeneration observed in Pld3.1 homozygous adults is suppressed by expression of rdgAScer\UAS.cRa under the control of Scer\GAL4ninaE.PU in the mutant background.

      (Thakur et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      rdgAScer\UAS.cRa
      rdgAUAS.cRa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Raghu
      Secondary FlyBase IDs
        References (3)