FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\pyrd06722
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General Information
Symbol
Dmel\pyrd06722
Species
D. melanogaster
Name
FlyBase ID
FBal0241098
Feature type
allele
Associated gene
Dmel\pyr
Associated Insertion(s)
P{XP}pyrd06722
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{XP}pyrd06722
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{XP}
    Regulatory region(s)
    UAS
    Also carries
    FRT
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Expression of pyrd06722 under the control of Scer\GAL4repo efficiently induces glial cell division and stimulates glial motility in the eye disc.

        When small clones of cells expressing pyrd06722 under the control of Scer\GAL4tub are induced ahead of the morphogenetic furrow in the eye disc, glial cells can migrate along these cells and are able to cross the morphogenetic furrow, which they never do in wild type.

        Clones in the apical peripodial membrane that are expressing pyrd06722 under the control of Scer\GAL4tub ectopically attract glial cells to the apical side of the eye disc.

        Expression of pyrd06722 under the control of Scer\GAL4GMR.long increases wrapping of the photoreceptor axons by glia.

        (Franzdóttir et al., 2009)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Suppressor of
        Statement
        Reference

        pyrd06722/Scer\GAL4GMR.long is a suppressor of glial cell phenotype of thse02026

        (Franzdóttir et al., 2009)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Expression of pyrd06722 under the control of Scer\GAL4GMR.long rescues the failure of thse02026/thse02026 glia to wrap photoreceptor axons.

        (Franzdóttir et al., 2009)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        pyrXP06722
        (Franzdóttir et al., 2009)
        pyrd06722
        Name Synonyms
        Secondary FlyBase IDs
          References (1)