FlyBase Allele Report: Dmel\p38b[JF03341]

General Information

Symbol

Dmel\p38b^JF03341

Species

D. melanogaster

Name

FlyBase ID

FBal0242513

Feature type

allele

Associated gene

Dmel\p38b

Associated Insertion(s)

Carried in Construct

P{TRiP.JF03341}

Also Known As

UAS-p38b-RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

(Perkins et al., 2009)

Progenitor genotype

Carried in construct

P{TRiP.JF03341}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-JF03341

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | larval stage | RU486 conditional, with Scer\GAL4^{elav.Switch.PO}

(Klinedinst et al., 2013)

Phenotype Manifest In

NMJ bouton | larval stage | RU486 conditional, with Scer\GAL4^{elav.Switch.PO}

(Klinedinst et al., 2013)

Detailed Description

Statement

Reference

Expression of p38b^JF03341 in the fat body under the control of Scer\GAL4^DcG results in significant hyperglycaemia.

(Ugrankar et al., 2015)

Expression of p38b^JF03341 under the control of Scer\GAL4^{elav.Switch.PO} (in the presence of RU486) results in an increase in maximum bouton diameter at the larval neuromuscular junction compared to controls.

(Klinedinst et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Suppressor of

Statement

Reference

p38b^JF03341/Scer\GAL4^ptc.PU is a non-suppressor of abnormal cell migration | third instar larval stage phenotype of Scer\GAL4^ptc.PU, lic^UAS.ORF

(Sun et al., 2019)

p38b^JF03341, Scer\GAL4^ptc.PU is a non-suppressor of abnormal cell migration | third instar larval stage phenotype of Hsap\MAP2K3^UAS.cSa, Scer\GAL4^ptc.PU

(Sun et al., 2019)

Phenotype Manifest In

NOT Suppressor of

Statement

Reference

p38b^JF03341/Scer\GAL4^ptc.PU is a non-suppressor of anterior-posterior compartment boundary of the wing disc | third instar larval stage phenotype of Scer\GAL4^ptc.PU, lic^UAS.ORF

(Sun et al., 2019)

p38b^JF03341, Scer\GAL4^ptc.PU is a non-suppressor of anterior-posterior compartment boundary of the wing disc | third instar larval stage phenotype of Hsap\MAP2K3^UAS.cSa, Scer\GAL4^ptc.PU

(Sun et al., 2019)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

29405

y¹ v¹; P{TRiP.JF03341}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

p38b^JF03341

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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