FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Rho1UAS.cHa
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General Information
Symbol
Dmel\Rho1UAS.cHa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Harden
FlyBase ID
FBal0244143
Feature type
allele
Associated gene
Dmel\Rho1
Associated Insertion(s)
Carried in Construct
P{UAS-Rho1.H}
Key Links
Transgenic product class
wild_type
(Xu et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Xu et al., 2008)
Mutagen
in vitro construct
(Xu et al., 2008)
Progenitor genotype
Carried in construct
P{UAS-Rho1.H}
Cytology
Description

UAS regulatory sequences drive expression of wild-type Rho1.

(Xu et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Rho1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Rho1Scer\UAS.cHa under the control of Scer\GAL4fkh.PH in a wild-type background has no effect on salivary gland invagination in embryos. Salivary gland migration is delayed at stage 12 in these embryos, however this delay in migration is corrected by stage 14.

      (Xu et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4fkh.PH/Rho1UAS.cHa partially rescues Rho11B

      (Xu et al., 2008)

      Scer\GAL4en-e16E/Rho1UAS.cHa partially rescues Rho11B

      (Xu et al., 2008)

      Rho1UAS.cHa/Scer\GAL4wg.PM partially rescues Rho11B

      (Xu et al., 2008)

      Scer\GAL4twi.PB/Rho1UAS.cHa partially rescues Rho11B

      (Xu et al., 2008)

      Scer\GAL4bap.PB/Rho1UAS.cHa partially rescues Rho11B

      (Xu et al., 2008)

      Scer\GAL4fkh.PH/Rho1UAS.cHa partially rescues Rho1k02107b

      (Xu et al., 2008)
      Comments

      Expression of Rho1Scer\UAS.cHa under the control of Scer\GAL4fkh.PH partially rescues the salivary gland defects of Rho1k02107b embryos; with the fraction of non-invaginated glands decreasing from 80% to 27% and the fraction of completely invaginated glands increasing from 2% to 58%.

      Expression of Rho1Scer\UAS.cHa under the control of one of Scer\GAL4fkh.PH, Scer\GAL4en-e16E or Scer\GAL4wg.PM partially rescues the salivary gland migration defects of Rho11B embryos, with the greatest rescue being seen when expression is driven by Scer\GAL4en-e16E.

      Expression of Rho1Scer\UAS.cHa under the control of one of either Scer\GAL4twi.PB or Scer\GAL4bap.PB partially rescues the salivary gland migration defects of Rho11B embryos.

      (Xu et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Rho1Scer\UAS.cHa
      Rho1UAS.cHa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Harden
      Secondary FlyBase IDs
        References (1)