FlyBase Allele Report: Scer\GAL4[NP5288]

General Information

Symbol

Scer\GAL4^NP5288

Species

S. cerevisiae

Name

FlyBase ID

FBal0245053

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

P{GawB}NP5288

Carried in Construct

Also Known As

NP5288, NP5288-GAL4

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{GawB}NP5288

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:14,458,195..14,458,453 [+]

(Israel and Parnas, 2025, Israel et al., 2022, Georganta et al., 2021, Son and Choi, 2020, Flybrain Neuron Database et al., 2018.6.28, Haynes et al., 2015, Tanaka et al., 2012, Pitman et al., 2011, Pauls et al., 2010, Okada et al., 2009, Tanaka et al., 2008)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult antennal lobe projection neuron

(Tanaka et al., 2008)

adult mushroom body anterior paired lateral cell

(Flybrain Neuron Database et al., 2018.6.28, Pitman et al., 2011, Tanaka et al., 2008)

adult mushroom body alpha-lobe

(Tanaka et al., 2008)

adult mushroom body beta-lobe

(Tanaka et al., 2008)

pedunculus of adult mushroom body

(Tanaka et al., 2008)

calyx of adult mushroom body

(Tanaka et al., 2008)

adult mushroom body dorsal accessory calyx

(Tanaka et al., 2008)

adult medial antennal lobe tract

(Tanaka et al., 2008)

projection neuron | subset

(Pitman et al., 2011)

adult brain | restricted

(Pitman et al., 2011)

adult mushroom body gamma-lobe

(Tanaka et al., 2008)

adult mushroom body beta'-lobe

(Tanaka et al., 2008)

adult mushroom body alpha'-lobe

(Tanaka et al., 2008)

unilateral antennal lobe projection neuron | subset

(Tanaka et al., 2012)

adult antennal lobe projection neuron D adPN

(Israel et al., 2022, Tanaka et al., 2012)

adult antennal lobe projection neuron DA2 lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DL1 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DL4 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DL5 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DM1 lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DM2 lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DM3 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DM4 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DM5 lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DM6 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VA2 adPN

(Israel et al., 2022, Tanaka et al., 2012)

adult antennal lobe projection neuron VA3 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VA4 lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VA6 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VM2 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VM3 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VM5d adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VM5v adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VA7l adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VC1 lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VC2 lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VM7v adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DA1 lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DA3 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DA4l adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DC3 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DL3 lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VA1d adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VA1v adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DC2 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VA7m lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VL2a adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VL2p lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VM1 lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VM4 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DP1m adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DL2v adPN

(Tanaka et al., 2012)

medial antennal lobe tract projection neuron 4 | subset

(Tanaka et al., 2012)

adult neuron | subset of adult ventral nerve cord

(Israel et al., 2022)

uniglomerular antennal lobe projection neuron | subset

(Israel et al., 2022)

adult antennal lobe projection neuron VA5 lPN

(Israel et al., 2022)

adult neuron | subset of adult subesophageal zone

(Israel et al., 2022)

Additional Information

Statement

Reference

ScerGAL4^NP5288 drives expression in around 65 uniglomerular and 3 multiglomerular antennal lobe projection neurons. The cell bodies of around 36 of these neurons are positioned in the anterior-dorsal part of the antennal lobe. Around 35 cell bodies are found in the lateral part and 7 to 8 are positioned ventrally. The uniglomerular neurons project to a large number of antennal lobe glomeruli including VM7d, DA4m, VP1 and VP4 while he multiglomerular neurons project to all glomeruli.

(Tanaka et al., 2012)

ScerGAL4^NP5288 is expressed in a subset of neurons in the adult brain, including projection neurons and the mushroom body anterior paired lateral cell. Use of GFP-reconstitution across synaptic partners (GRASP) reveals that there are close contacts between the terminals of the mushroom body dorsal and anterior paired medial cells in the mushroom body alpha'/beta' lobes and in the pedunculus.

(Pitman et al., 2011)

Marker for

adult antennal lobe projection neuron

(Tanaka et al., 2008)

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal memory | heat sensitive, with shi^1.UAS

(Pitman et al., 2011)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

104937

y^* w^*; P{GawB}NP5288 / CyO, P{UAS-lacZ.UW14}UW14

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^NP5288

Name Synonyms

Secondary FlyBase IDs

References (11)

Report Sections

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