FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ppk28UAS.cCa
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General Information
Symbol
Dmel\ppk28UAS.cCa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Cameron
FlyBase ID
FBal0245233
Feature type
allele
Associated gene
Dmel\ppk28
Associated Insertion(s)
Carried in Construct
P{UAS-ppk28.C}
Key Links
Transgenic product class
wild_type
(Cameron et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Cameron et al., 2010)
Mutagen
in vitro construct
(Cameron et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-ppk28.C}
Cytology
Description

UASt regulatory sequences drive expression of full-length ppk28 transcript variant a.

(Cameron et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
ppk28
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Extracellular bristle recordings of i-type labellar taste sensilla that are expressing ppk28Scer\UAS.cCa under the control of Scer\GAL4Gr66a.3.153 show a response to water, in contrast to controls. The response is blunted as the solute concentration is increased, with both N-methyl-D-glucamine and sucrose producing dose-sensitive response decreases in the mutant sensilla.

      (Cameron et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      ppk28UAS.cCa/Scer\GAL4ppk28.PC partially rescues ppk28Δ

      (Cameron et al., 2010)
      Comments

      The electrophysiological response of l-type labellar taste sensilla to water is partially restored in ppk28Δ animals by expression of ppk28Scer\UAS.cCa under the control of Scer\GAL4ppk28.PC. The rescued flies also show normal water consumption (as assayed by the drinking time).

      (Cameron et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      ppk28Scer\UAS.cCa
      ppk28UAS.cCa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Cameron
      Secondary FlyBase IDs
        References (1)