FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4ppk28.PC
Open Close
General Information
Symbol
Scer\GAL4ppk28.PC
Species
S. cerevisiae
Name
pickpocket 28 promoter construct of Cameron
FlyBase ID
FBal0245232
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{ppk28-GAL4.C}
Also Known As
ppk28-GAL4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Cameron et al., 2010)
Progenitor genotype
Carried in construct
P{ppk28-GAL4.C}
Cytology
Description

A 1.00kb upstream fragment of ppk28 (coordinates 16699333-16700336, GenBank accession NC_004354.3) is fused upstream of sequence encoding a GAL4 driver.

(Cameron et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
ppk28
ppk28_promoter-Gal4
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      water-sensing neuron of labellar taste bristle
      (Cameron et al., 2010)
      gustatory receptor neuron | subset of labellar taste bristle
      (Cameron et al., 2010)
      chemosensory neuron of adult labral sensillum 7 | subset
      (Joseph et al., 2017)
      water-sensing neuron
      (Zhang et al., 2020)
      Additional Information
      Statement
      Reference

      ScerGAL4ppk28.PC drives expression in a single chemosensory neuron of adult labral sensillum 7.

      (Joseph et al., 2017)

      Drives expression in water-sensing neurons.

      (FlyBase Curators, 2017)

      ScerGAL4ppk28.PC labels the water-sensing neurons (W cell) of the taste bristles of the proboscis. Gustatory receptor neurons labeled with ScerGAL4ppk28.PC do not overlap with expression of AvicGFPGr66a.3x.IRES.2x or AvicGFPGr5a.3x.IRES.2x in the proboscis, which label the bitter and sugar-sensitive neurons, respectively. The projection of the neurons labeled with ScerGAL4ppk28.PC enter the subesophageal ganglion via the labellar nerve and the labial nerve. In the former nerve there is some overlap with projections labeled with AvicGFPGr5a.3x.IRES.2x. Almost all cells labeled with ScerGAL4ppk28.PC are also labeled by the expression of ppk28 transcript. Most taste bristles that express ScerGAL4ppk28.PC are labeled by ScerGAL4NP1017.

      (Cameron et al., 2010)
       
      Marker for
      water-sensing neuron
      (Zhang et al., 2020)
      water-sensing neuron of labellar taste bristle
      (Cameron et al., 2010)
      Reflects expression of
      ppk28
      (Zhang et al., 2020, Joseph et al., 2017, Cameron et al., 2010)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (using Ctet\tetXTNT-LC.UAS) of Scer\GAL4ppk28.PC cells in starved adult males significantly reduces preference for softer sucrose-containing agarose, compared to controls.

      (Sánchez-Alcañiz et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Scer\GAL4ppk28.PC
      Name Synonyms
      pickpocket 28 promoter construct of Cameron
      Secondary FlyBase IDs
        References (33)