FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4Gr28b.c.PT
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General Information
Symbol
Scer\GAL4Gr28b.c.PT
Species
S. cerevisiae
Name
FlyBase ID
FBal0245243
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{Gr28b.c-GAL4}
Also Known As
Gr28b.c-Gal4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Thorne and Amrein, 2008)
Progenitor genotype
Carried in construct
P{Gr28b.c-GAL4}
Cytology
Description

A 1326bp fragment containing the promoter region immediately upstream of the c-isoform of Gr28b regulates expression of a GAL4 driver.

(Thorne and Amrein, 2008)
Allele components
Component
Use(s)
Regulatory region(s)
Gr28b
Gr28b_Gr28b.c
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage
      embryonic/larval oenocyte | faint
      (Thorne and Amrein, 2008)
      larval stage
      terminal organ | restricted
      (Thorne and Amrein, 2008)
      third instar larval stage
      larval ventral nerve cord | restricted
      (Mishra et al., 2018)
      multidendritic neuron | subset
      (Mishra et al., 2018)
      embryonic/larval midgut | restricted
      (Mishra et al., 2018)
      adult stage
      gustatory receptor neuron | subset
      (Thorne and Amrein, 2008)
      gustatory receptor neuron of labellar taste bristle | subset
      (Thorne and Amrein, 2008)
      gustatory receptor neuron of short labellar taste bristle | subset
      (Thorne and Amrein, 2008)
      gustatory receptor neuron of intermediate labellar taste bristle | subset
      (Thorne and Amrein, 2008)
      gustatory receptor neuron | subset of labral sense organ neuron
      (Thorne and Amrein, 2008)
      gustatory receptor neuron | subset of adult labral sense organ
      (Thorne and Amrein, 2008)
      gustatory receptor neuron | subset of ventral cibarial sense organ
      (Thorne and Amrein, 2008)
      gustatory receptor neuron | subset of dorsal cibarial sense organ
      (Thorne and Amrein, 2008)
      gustatory receptor neuron | faint | subset of prothoracic tarsal segment 5
      (Thorne and Amrein, 2008)
      neuron | faint | subset of prothoracic tarsal segment 5
      (Thorne and Amrein, 2008)
      maxillary palp | restricted
      (Thorne and Amrein, 2008)
      Johnston organ neuron | subset
      (Thorne and Amrein, 2008)
      campaniform sensillum | subset of wing vein L3
      (Thorne and Amrein, 2008)
      campaniform sensillum | subset of wing vein L1
      (Thorne and Amrein, 2008)
      mechanosensory neuron | subset of leg
      (Thorne and Amrein, 2008)
      prothoracic femoral chordotonal organ
      (Thorne and Amrein, 2008)
      metathoracic femoral chordotonal organ
      (Thorne and Amrein, 2008)
      mesothoracic femoral chordotonal organ
      (Thorne and Amrein, 2008)
      dendritic arborizing neuron | subset of abdomen | dorsal
      (Thorne and Amrein, 2008)
      gnathal ganglion | restricted
      (Thorne and Amrein, 2008)
      multidendritic neuron
      (Thorne and Amrein, 2008)
      adult antennal lobe | restricted
      (Thorne and Amrein, 2008)
      bitter-sensitive labellar taste bristle
      (Sang et al., 2019)
      short labellar taste bristle S-c
      (Sang et al., 2019)
      short labellar taste bristle
      (Sang et al., 2019)
      short labellar taste bristle S-a
      (Sang et al., 2019)
      short labellar taste bristle S-b
      (Sang et al., 2019)
      intermediate labellar taste bristle
      (Sang et al., 2019)
      intermediate labellar taste bristle I-b
      (Sang et al., 2019)
      Additional Information
      Statement
      Reference

      Expression of ScerGAL4Gr28b.c.PT is seen in approximately 45 neurons per labial palp. ScerGAL4Gr28b.c.PT is found to be expressed in single neurons associated with the ventral cibarial sense organ, dorsal cibarial sense organ and the labral sense organ. Expression is found in at least two taste neurons and also in several non-chemosensory neurons associated with the fifth tarsal segment. Expression of ScerGAL4Gr28b.c.PT is seen in a single, large cell at the base of the maxillary palpus that is not an olfactory sensory neuron. Expression is seen in approximately 5 neurons of, or near, the Johnston's organ. Expression of ScerGAL4Gr28b.c.PT is seen in leg neurons thought to be stretch receptors or proprioreceptors. Expression of ScerGAL4Gr28b.c.PT is seen in multidendritic neurons of all abdominal segments of the larvae.

      (Thorne and Amrein, 2008)
       
      Marker for
      Reflects expression of
      Gr28b
      (Sang et al., 2019, Thorne and Amrein, 2008)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4Gr28b.c.PT
      Name Synonyms
      Secondary FlyBase IDs
        References (5)