R541H | sax-PA; R506H | sax-PB; R553H | sax-PC
A missense mutation altering a highly conserved Arg residue in the cytoplasmic kinase domain.
Amino acid replacement: R541H.
abnormal developmental rate | larval stage (with Df(2R)H23)
abnormal size | larval stage (with Df(2R)H23)
lethal (with Df(2R)H23)
lethal (with Df(2R)sax1rv2)
lethal (with Df(2R)sax-H9)
lethal (with sax1rv1)
lethal (with sax1rv5)
lethal (with sax3)
lethal (with sax5)
lethal | larval stage (with sax4)
lethal | P-stage (with sax4)
partially lethal - majority die (with saxP)
viable (with sax1)
viable (with sax2)
brain | larval stage (with Df(2R)H23)
imaginal disc (with Df(2R)H23)
trachea | larval stage (with Df(2R)H23)
Less than 5% of sax6/Df(2R)H23 hemizygous mutant larvae exhibit developmental delay, lethargy, a reduction in the size of imaginal discs, brain | larval stage, and midgut structures, as well as trachea | larval stagel truncations.
dpphr4/dpp[+], sax6 has partially lethal - majority live | dominant | maternal effect phenotype
When sax6/+ females are crossed to dpphr4/+ males, the resulting dpphr4/+ progeny show a moderate drop in viability compared to the dpphr4/+ progeny of wild-type mothers in control crosses.
sax6/Df(2R)sax-H9 is rescued by saxhs.PB