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General Information
Symbol
Dmel\l(2)gd124
Species
D. melanogaster
Name
FlyBase ID
FBal0246239
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Nucleotide change:

C11108878T

Amino acid change:

P557S | l(2)gd1-PA; P557S | l(2)gd1-PB

Reported amino acid change:

P557S

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: P557S.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

l(2)gd124 mutant flies show missing and abnormal external sensory organs, consisting of four sockets but no hair cells. Mutant heads are significantly enlarged.

Postorbital bristles from l(2)gd124 mutant clones display multiple sockets but no hairs.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference

l(2)gd124 has visible phenotype, suppressible by HrsD28

Other
Statement
Reference
Phenotype Manifest In
Suppressed by
Statement
Reference
Other
Additional Comments
Genetic Interactions
Statement
Reference

The external sensory organ multi-socket phenotype in l(2)gd124 animals is suppressed in a HrsD28 mutant background.

A postorbital bristle multiple socket phenotype is not observed when Nl1N-ts1 is inactivated in a l(2)gd124 mutant eye clones.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (1)