Deletion that removes most of the ST6Gal coding sequence. The design of the targeting construct used to generate this allele was aimed at creating a mutant allele with Avic\GFP expression driven by the ST6Gal promoter (by inserting the Avic\GFP coding sequence), however the Avic\GFP coding sequence was damaged by a short insertion of approximately 30bp during the targeting event, and there is no Avic\GFP expression in the mutant.
Homozygous ST6GalL22 enhances the paralysis defect seen in Csas21 mutant flies at elevated temperatures. The time of onset of paralysis is shorter than in either Csas21 or ST6GalL22 mutants alone. One copy of ST6GalL22 does not enhance the homozygous Csas21 phenotype, and one copy of Csas21 is insufficient to enhance the ST6GalL22 mutant phenotype.
ST6GalL22/ST6GalS23 enhances the locomotor defects seen in CsasMB04236/Df(3L)XS2182 mutant flies. The time taken for flies to right themselves after being knocked over is extended compared to either mutant alone.